Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | C5 | P01031 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131676 | 0.74 | LMNA (0.47) | MEN1KMT2AMAPTARALDH1A1 | |
| SCHEMBL8580035 | 0.71 | FFAR1 (0.45) | PTGS2MEN1PTGS1KMT2AMAPT | |
| SCHEMBL3639561 | 0.71 | FFAR1 (0.45) | PTGS2MEN1PTGS1KMT2AMAPT | |
| SCHEMBL7234600 | 0.71 | F7 (0.58) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL3558857 | 0.71 | CYP2A6 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL15741304 | 0.70 | MTNR1A (0.45) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL1253014 | 0.69 | KDM4E (0.54) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL24813005 | 0.68 | SPR (0.53) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL30708185 | 0.68 | SPR (0.53) | PTGS2MEN1PTGS1KMT2AABCC4 | |
| SCHEMBL11458159 | 0.67 | ALDH1A1 (0.56) | PTGS2MEN1KMT2AMAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891067-B1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARM INC (US) | 2016-01-13 | — | — | EP | disclosed |