SCHEMBL17416872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17416879	0.82	PKM (0.50)	HSD17B10RNASEH1KDM4E
	SCHEMBL21093498	0.77	HSD17B10 (0.40)	TSHRHSD17B10ADORA2AADORA1POLB
	SCHEMBL23089138	0.73	KDM4E (0.40)	RNASEH1KDM4EMAPK1
	SCHEMBL19350458	0.73	GAA (0.46)	HSD17B10POLBMEN1KMT2ACYP3A4
	SCHEMBL5883374	0.72	L3MBTL1 (0.42)	TSHRHSD17B10MEN1KMT2ACYP3A4
	SCHEMBL17422001	0.72	TTR (0.48)	TSHRRNASEH1CYP3A4KDM4E
	SCHEMBL30726836	0.72	TTR (0.48)	TSHRRNASEH1CYP3A4KDM4E
	SCHEMBL17416886	0.72	MAPT (0.37)	TSHRHSD17B10ADORA2AADORA1POLB
	SCHEMBL22116821	0.71	TSHR (0.50)	TSHRHSD17B10POLBMEN1KMT2A
	SCHEMBL9048230	0.71	CA12 (0.62)	TSHRHSD17B10POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.