SCHEMBL17416879

SCHEMBL17416879

COc1cc(Br)nc(C(=O)O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
PTGS2 P35354 3/20 0.47
ALOX5 P09917 1/20 0.46
RNASEH1 O60930 1/20 0.45
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
IGFBP3 P17936 2/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17416872 0.82 TSHR (0.47) RNASEH1KDM4EHSD17B10
SCHEMBL19350458 0.80 GAA (0.46) GAALMNAALDH1A1HPGDHSD17B10
SCHEMBL19283132 0.79 PKM (0.50) PKMCA12CA1CA2CA3
SCHEMBL23089138 0.77 KDM4E (0.40) RNASEH1KDM4EALDH1A1
SCHEMBL30726836 0.76 TTR (0.48) RNASEH1KDM4EALDH1A1PIM1
SCHEMBL17422001 0.76 TTR (0.48) RNASEH1KDM4EALDH1A1PIM1
SCHEMBL15270753 0.75 KDM4E (0.47) CA12CA1CA2CA4CA6
SCHEMBL17422690 0.74 PTGS2 (0.47) PKMCA12CA1CA2CA3
SCHEMBL6508768 0.72 ERN1 (0.49) PKMCA12CA1CA2CA3
SCHEMBL4684362 0.71 MEN1 (0.49) KDM4EGAALMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3166611-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-09-16 EP disclosed
EP-3166611-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-09-16 EP disclosed
EP-3422855-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-07-08 EP disclosed
CN-106573005-B Process for preparing 4-alkoxy-3-hydroxypicolinic acid 美国陶氏益农公司 2020-05-29 CN disclosed
CN-106659724-B Process for preparing 4-alkoxy-3-hydroxypicolinic acid 美国陶氏益农公司 2020-04-28 CN disclosed
EP-3166927-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-04-22 EP disclosed
EP-3166927-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2020-04-22 EP disclosed
EP-3166612-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2019-06-12 EP disclosed
EP-3166612-B1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2019-06-12 EP disclosed
EP-3422855-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS Dow Agrosciences LLC (US) 2019-01-09 EP disclosed
US-20160009676-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
US-20160009676-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
US-20160009649-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
US-20160009649-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
US-20160009649-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
US-20160009676-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
WO-2016007638-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS DOW AGROSCIENCES LLC (US) 2016-01-14 WO disclosed
US-20160009650-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
US-20160009650-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed
US-20160009650-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS CORTEVA AGRISCIENCE LLC 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160009649-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS HAAO, HPD, PAH PKM 2482/4885CA12 849/4885CA1 1159/4885
US-20160009650-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS HPD, HAAO, BLVRB PKM 3599/4885CA12 981/4885CA1 1261/4885
US-20160009676-A1 PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-HYDROXYPICOLINIC ACIDS HPD, HAAO, BLVRB PKM 3599/4885CA12 981/4885CA1 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.