Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020896 | 0.92 | SIRT6 (0.54) | SIRT5TLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL18291772 | 0.90 | SIRT6 (0.45) | SIRT5TLR2SIRT6SIRT1NMT2 | |
| SCHEMBL13997929 | 0.87 | SIRT5 (0.46) | SIRT5TLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL12519427 | 0.87 | GNAI3 (0.52) | SIRT5TLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL25841978 | 0.87 | FOLH1 (0.47) | TLR2SIRT6SIRT1NOD1 | |
| SCHEMBL24817235 | 0.83 | TLR2 (0.52) | SIRT5TLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL14004794 | 0.83 | SIRT6 (0.42) | TLR2SIRT6SIRT1NMT2NMT1 | |
| SCHEMBL24155382 | 0.83 | KISS1R (0.45) | SIRT5TLR2SIRT6SIRT1NMT2 | |
| SCHEMBL24155383 | 0.83 | KISS1R (0.45) | SIRT5TLR2SIRT6SIRT1NMT2 | |
| SCHEMBL24155380 | 0.83 | KISS1R (0.45) | SIRT5TLR2SIRT6SIRT1NMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234007-B2 | RGD mimetic γ-AApeptides and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-01-12 | — | — | US | disclosed |