Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891049 | 0.91 | PKM (0.60) | PKMTHRBHTTATMMAPT | |
| SCHEMBL8538203 | 0.89 | ATM (0.68) | PKMTHRBHTTATMMAPT | |
| SCHEMBL903628 | 0.89 | ATM (0.68) | PKMTHRBHTTATMMAPT | |
| SCHEMBL6503711 | 0.89 | PKM (0.57) | PKMTHRBHTTATMMAPT | |
| SCHEMBL5991929 | 0.89 | ALDH1A1 (0.74) | PKMTHRBHTTATMMAPT | |
| SCHEMBL6506349 | 0.87 | ALDH1A1 (0.64) | PKMTHRBHTTATMMAPT | |
| SCHEMBL15199327 | 0.86 | ALDH1A1 (0.56) | PKMTHRBHTTATMMAPT | |
| SCHEMBL12949944 | 0.86 | ATM (0.64) | PKMTHRBHTTATMMAPT | |
| SCHEMBL16143376 | 0.86 | ATM (0.56) | PKMTHRBHTTATMMAPT | |
| SCHEMBL8538518 | 0.85 | ALDH1A1 (0.66) | PKMTHRBHTTATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815772-B2 | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof | BIOCON LIMITED (IN) | 2017-11-14 | — | — | US | disclosed |
| US-20160009634-A1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LIMITED (IN) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009634-A1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | ADH1C, DRD2, ADH1A | PKM 2711/4885THRB 4402/4885HTT 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.