SCHEMBL17430487

SCHEMBL17430487

COc1ccc(C2=c3cc4cc5c(cc4cc3OC2=O)=C(c2ccc(C)cc2)C(=O)O5)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.45
ALKBH3 Q96Q83 2/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
KCNA5 P22460 1/20 0.42
KCNH2 Q12809 1/20 0.42
ACHE P22303 1/20 0.42
EDNRA P25101 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MAPT P10636 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALOX5 P09917 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
ME2 P23368 1/20 0.40
ME1 P48163 1/20 0.40
ME3 Q16798 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17430470 0.99 MAOB (0.44) MAOBALKBH3KMT2AMEN1KCNA5
SCHEMBL17432766 0.94 ME2 (0.44) MAOBNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL17430475 0.93 ALKBH3 (0.47) MAOBALKBH3KMT2AMEN1KCNA5
SCHEMBL17432764 0.93 ME2 (0.42) MAOBNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL17432753 0.87 ME2 (0.47) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL8089080 0.82 BACE1 (0.47) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL17430488 0.81 GSTP1 (0.47) MAOBALKBH3KCNA5KCNH2NPC1
SCHEMBL17432762 0.78 GSTP1 (0.53) MAOBNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL17430479 0.77 KCNA5 (0.45) MAOBALKBH3KMT2AMEN1KCNA5
SCHEMBL26414058 0.77 PTGS2 (0.45) MAOBKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170062746-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2017-03-02 US disclosed
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160013426-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING DEVICE, OPTICAL SENSOR, AND METHOD OF USING PHOTOELECTRIC CONVERSION ELEMENT PPOX, PIN4, CRY1 MAOB 1824/4885ALKBH3 1178/4885KMT2A 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.