SCHEMBL17430706

SCHEMBL17430706

Cc1ccc(N(c2ccc(C)cc2)c2ccc(N(c3ccccc3)c3ccc4c(c3)CC4)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.39
▸ MAPT P10636 3/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ APP P05067 1/20 0.39
▸ HTR2C P28335 1/20 0.36
▸ HTR2B P41595 1/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ NPC1 O15118 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ NFKB1 P19838 1/20 0.36
▸ NFKB2 Q00653 1/20 0.36
▸ RELA Q04206 1/20 0.36
▸ CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13868392 0.93 DPP4 (0.40) ALDH1A1MAPTL3MBTL1CYP2C19KDM4E
SCHEMBL13174481 0.93 ALDH1A1 (0.39) ALDH1A1MAPTL3MBTL1CYP2C19TDP1
SCHEMBL24159881 0.93 ALDH1A1 (0.39) ALDH1A1MAPTL3MBTL1CYP2C19TDP1
SCHEMBL2607300 0.93 ALDH1A1 (0.39) ALDH1A1MAPTL3MBTL1CYP2C19TDP1
SCHEMBL12606451 0.92 KCNA1 (0.37) ALDH1A1MAPTL3MBTL1CYP2C19KDM4E
SCHEMBL14506990 0.91 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1CYP2C19KDM4E
SCHEMBL11898477 0.91 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1CYP2C19KDM4E
SCHEMBL17841771 0.91 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1CYP2C19KDM4E
SCHEMBL13241965 0.88 ALDH1A1 (0.38) ALDH1A1MAPTL3MBTL1CYP2C19KDM4E
SCHEMBL11950306 0.87 ALDH1A1 (0.36) ALDH1A1MAPTL3MBTL1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180123056-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-03 — — US disclosed
US-20180022990-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-25 — — US disclosed
US-20170283546-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-05 — — US disclosed
US-20170253795-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-07 — — US disclosed
US-9741934-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-22 — — US disclosed
US-20170222163-A1 LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 — — US disclosed
US-20170194584-A1 LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-06 — — US disclosed
US-20170117491-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED IN THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-27 — — US disclosed
US-20170092864-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-30 — — US disclosed
US-20170040542-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-09 — — US disclosed
US-20170040538-A1 LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-09 — — US disclosed
US-9530966-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-27 — — US disclosed
US-20160013418-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-01-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170117491-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED IN THE SAME CYBA, CRY1, AP2A1 ALDH1A1 8/4885MAPT 1007/4885L3MBTL1 1449/4885
US-20170040542-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME CRY1, CHRM1, CRY2 ALDH1A1 407/4885MAPT 2569/4885L3MBTL1 1044/4885
US-20170092864-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME CRY1, CCNA1, H1-0 ALDH1A1 233/4885MAPT 2698/4885L3MBTL1 368/4885
US-20170040538-A1 LIGHT-EMITTING DEVICE CRY1, CRY2, CYBA ALDH1A1 963/4885MAPT 1283/4885L3MBTL1 962/4885
US-20170194584-A1 LIGHT EMITTING DEVICE CRY1, CCNE2, L1CAM ALDH1A1 63/4885MAPT 2910/4885L3MBTL1 86/4885
US-20180123056-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE CHRM1, CRY1, L1CAM ALDH1A1 59/4885MAPT 1420/4885L3MBTL1 280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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