Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL553389 | 0.97 | DNM1 (0.45) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Phosphine SCHEMBL27384096 | 0.93 | DNM1 (0.43) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| SCHEMBL29531465 | 0.93 | DNM1 (0.47) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Iodide SCHEMBL27474337 | 0.90 | DNM1 (0.41) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Iodide SCHEMBL27547544 | 0.90 | DNM1 (0.41) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Hydrogen Sulfide SCHEMBL16734975 | 0.90 | DNM1 (0.45) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Water SCHEMBL553358 | 0.90 | DNM1 (0.45) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Bromide SCHEMBL1003648 | 0.90 | DNM1 (0.50) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Fluoride Ion SCHEMBL15738678 | 0.90 | DNM1 (0.45) | DNM1OPRM1TSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL227335 | 0.90 | DNM1 (0.45) | DNM1OPRM1TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718754-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-08-01 | — | — | US | claimed |
| US-9714206-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-07-25 | — | — | US | claimed |
| US-20160251292-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-09-01 | — | — | US | claimed |
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | claimed |
| US-20160185700-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | claimed |
| US-9365479-B1 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2016-06-14 | — | — | US | claimed |
| US-9718754-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-08-01 | — | — | US | disclosed |
| US-9714206-B2 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160251292-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-09-01 | — | — | US | disclosed |
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| US-20160185700-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| US-9365479-B1 | Methyl-iodide-free carbonylation of an alcohol to its homologous aldehyde and/or alcohol | EASTMAN CHEMICAL COMPANY (US) | 2016-06-14 | — | — | US | disclosed |
| US-9266807-B1 | Conversion of alcohols to longer chain aldehydes or alcohols | EASTMAN CHEMICAL COMPANY (US) | 2016-02-23 | — | — | US | disclosed |
| US-9238606-B1 | Methyl-Iodide-free carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185701-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | ADH1C, ADH5, ADH1A | DNM1 3478/4885OPRM1 187/4885TSHR 1031/4885 |
| US-20160251292-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | ADH1C, ADH5, ADH1A | DNM1 3463/4885OPRM1 175/4885TSHR 1519/4885 |
| US-20160185700-A1 | METHYL-IODIDE-FREE CARBONYLATION OF AN ALCOHOL TO ITS HOMOLOGOUS ALDEHYDE AND/OR ALCOHOL | ADH1C, ADH5, ADH1A | DNM1 3463/4885OPRM1 175/4885TSHR 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.