Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 1.00 |
| ▸ | NQO2 | P16083 | 3/20 | 1.00 |
| ▸ | NQO1 | P15559 | 1/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 0.75 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.73 |
| ▸ | TTR | P02766 | 2/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.72 |
| ▸ | MYC | P01106 | 1/20 | 0.72 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.71 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.71 |
| ▸ | TUBB | P07437 | 2/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966533 | 1.00 | ALOX5 (1.00) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL1743354 | 1.00 | ALOX5 (1.00) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL28444241 | 0.93 | ALOX5 (0.88) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL28445854 | 0.93 | ALOX5 (0.88) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL6781119 | 0.88 | NQO2 (0.78) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL6781126 | 0.88 | NQO2 (0.78) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL16307442 | 0.87 | ALOX5 (0.76) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL25328702 | 0.86 | ALOX5 (1.00) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL25328697 | 0.86 | ALOX5 (1.00) | ALOX5NQO2NQO1APPTUBB1 | |
| SCHEMBL3390342 | 0.86 | APP (1.00) | ALOX5NQO2NQO1APPTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172512-B | A group of compounds with similar cajanin structure, preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-08-03 | — | — | CN | claimed |
| CN-105030750-A | Application of longistyline structural analogues in prevention of hepatitis C virus and acquired immune deficiency syndrome (AIDS) virus | INST MED BIOTECHNOLOGY CAMS | 2015-11-11 | — | — | CN | claimed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | claimed |
| EP-2796442-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2014-10-29 | — | — | EP | claimed |
| CN-103172512-A | A group of compounds with similar cajanin structure, preparation method and application | INST MEDICINAL BIOTECHNOLOGY | 2013-06-26 | — | — | CN | claimed |
| US-20210115007-A1 | STREPTOCOCCUS MUTANS GLUCOSYL TRANSFERASE INHIBITORS FOR DENTAL CARIES THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-04-22 | — | — | US | disclosed |
| WO-2019195430-A1 | STREPTOCOCCUS MUTANS GLUCOSYL TRANSFERASE INHIBITORS FOR DENTAL CARIES THERAPY | UAB RESEARCH FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |
| CN-105030750-B | Application of one group of cajanin structurally similar compounds in anti-hepatitis C virus and anti AIDS virus | 中国医学科学院医药生物技术研究所 | 2018-08-28 | — | — | CN | disclosed |
| CN-103172512-B | A group of compounds with similar cajanin structure, preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-08-03 | — | — | CN | disclosed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | disclosed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | disclosed |
| CN-105030750-A | Application of longistyline structural analogues in prevention of hepatitis C virus and acquired immune deficiency syndrome (AIDS) virus | INST MED BIOTECHNOLOGY CAMS | 2015-11-11 | — | — | CN | disclosed |
| WO-2011141458-A1 | POLYSUBSTITUTED BENZOFURANS AND MEDICINAL APPLICATIONS THEREOF | IKERCHEM, S.L. (ES) | 2011-11-17 | — | — | WO | disclosed |
| US-8038466-B1 | Power receptacle with enlarged heat dissipation path formed on mating face and power connector assembly thereof | ALLTOP ELECTRONICS (SUZHOU) CO., LTD (CN) | 2011-10-18 | — | — | US | disclosed |
| US-20100310615-A1 | COMPOSITIONS COMPRISING STILBENE POLYPHENOL DERIVATIVES AND USE THEREOF FOR COMBATING THE AGEING OF LIVING ORGANISMS AND DISEASES AFFECTING SAME | CAUDALIE (FR) | 2010-12-09 | — | — | US | disclosed |
| US-20100310615-A1 | COMPOSITIONS COMPRISING STILBENE POLYPHENOL DERIVATIVES AND USE THEREOF FOR COMBATING THE AGEING OF LIVING ORGANISMS AND DISEASES AFFECTING SAME | CAUDALIE (FR) | 2010-12-09 | — | — | US | disclosed |
| WO-2008131320-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | HDGF, TIE1, VEGFA | ALOX5 1084/4885NQO2 4026/4885NQO1 1746/4885 |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | ACHE, GAP43, LNPK | ALOX5 2183/4885NQO2 4644/4885NQO1 3634/4885 |
| US-20210115007-A1 | STREPTOCOCCUS MUTANS GLUCOSYL TRANSFERASE INHIBITORS FOR DENTAL CARIES THERAPY | UGGT1, UGCG, GLA | ALOX5 1521/4885NQO2 389/4885NQO1 912/4885 |
| US-20100310615-A1 | COMPOSITIONS COMPRISING STILBENE POLYPHENOL DERIVATIVES AND USE THEREOF FOR COMBATING THE AGEING OF LIVING ORGANISMS AND DISEASES AFFECTING SAME | PPARG, PPARA, PC | ALOX5 203/4885NQO2 467/4885NQO1 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.