Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.67 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.67 |
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502897 | 1.00 | CES1 (0.67) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL30762476 | 0.80 | ALDH1A1 (1.00) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL3093670 | 0.80 | TGM2 (0.67) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL10679123 | 0.80 | ALDH1A1 (1.00) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL3737904 | 0.80 | CES1 (0.62) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL1274994 | 0.80 | CES1 (1.00) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL3737886 | 0.80 | TGM2 (0.67) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL29451126 | 0.80 | CES1 (1.00) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL18702831 | 0.79 | CES1 (0.61) | CES1ALDH1A1ALDH2ALDH3A1DAO | |
| SCHEMBL3088899 | 0.77 | CES1 (0.59) | CES1ALDH1A1ALDH2ALDH3A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-7204857-B1 | Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL S.A. (FR) | 2007-04-17 | — | — | US | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| US-6114540-A | COMBINATORIAL LIBRARIES | ARQULE, INC. (US) | 2000-09-05 | — | — | US | claimed |
| US-12322757-B2 | Isatin derivative redoxamer for electrochemical device | UCHICAGO ARGONNE, LLC (US) | 2025-06-03 | — | — | US | disclosed |
| CN-114890947-B | Aromatic heterocyclic compound containing quinoline structural unit, and preparation method and application thereof | 郑州大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-117700407-A | 3, 3-disubstituted indol-2-one compound and preparation method and application thereof | 五邑大学 | 2024-03-15 | — | — | CN | disclosed |
| US-20230327205-A1 | ISATIN DERIVATIVE REDOXAMER FOR ELECTROCHEMICAL DEVICE | UCHICAGO ARGONNE, LLC. (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230327205-A1 | ISATIN DERIVATIVE REDOXAMER FOR ELECTROCHEMICAL DEVICE | UCHICAGO ARGONNE, LLC. (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230327205-A1 | ISATIN DERIVATIVE REDOXAMER FOR ELECTROCHEMICAL DEVICE | UCHICAGO ARGONNE, LLC. (US) | 2023-10-12 | — | — | US | disclosed |
| US-11715844-B2 | Isatin derivative redoxmer for electrochemical device | UCHICAGO ARGONNE, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| WO-1999012904-A1 | SPIRO[PYRROLIDINE-2,3'-OXINDOLE] COMPOUNDS AND METHODS OF USE | ARQULE, INC. (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5866396-A | REMOVAL OF BY-PRODUCTS USING ENZYMES | WEYLER WALTER (US) | 1999-02-02 | — | — | US | disclosed |
| CN-1202933-A | Improved microbial production of indigo | GENENCOR INT (US) | 1998-12-23 | — | — | CN | disclosed |
| WO-1998013474-A1 | MICROORGANISMS WITH ABILITY TO DEGRADE INDOLE AND ENZYMES THEREFROM | GENENCOR INTERNATIONAL, INC. (US) | 1998-04-02 | — | — | WO | disclosed |
| WO-1997019175-A1 | IMPROVED MICROBIAL PRODUCTION OF INDIGO | GENENCOR INTERNATIONAL, INC. (US) | 1997-05-29 | — | — | WO | disclosed |
| US-4267333-A | Preparation of 2-trifluoromethyl cinchoninic acids | UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4251661-A | Preparation of 2-trifluoromethyl cinchoninic acids | UNION CARBIDE CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | CES1 3158/4885ALDH1A1 83/4885ALDH2 110/4885 |
| US-20230327205-A1 | ISATIN DERIVATIVE REDOXAMER FOR ELECTROCHEMICAL DEVICE | NDUFS5, SQOR, NDUFS7 | CES1 4583/4885ALDH1A1 1221/4885ALDH2 163/4885 |
| US-12322757-B2 | Isatin derivative redoxamer for electrochemical device | NDUFS5, SQOR, NDUFS7 | CES1 4583/4885ALDH1A1 1221/4885ALDH2 163/4885 |
| US-11715844-B2 | Isatin derivative redoxmer for electrochemical device | SQOR, SLC39A14, NDUFS5 | CES1 4335/4885ALDH1A1 630/4885ALDH2 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.