SCHEMBL1745253

SCHEMBL1745253

C=C(c1ccccc1)c1cccc(CO)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 2/20 0.53
PRSS2 P07478 2/20 0.53
PRSS3 P35030 2/20 0.53
TSHR P16473 2/20 0.50
CNR2 P34972 1/20 0.44
ENPP2 Q13822 1/20 0.42
CFTR P13569 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
FOLH1 Q04609 1/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
XBP1 P17861 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GRM2 Q14416 1/20 0.39
PRKCI P41743 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30420527 1.00 PRSS1 (0.53) PRSS1PRSS2PRSS3TSHRCNR2
SCHEMBL5991861 0.82 TP53 (0.48) PRSS1PRSS2PRSS3CNR2MEN1
SCHEMBL27140587 0.82 TRPA1 (0.48) PRSS1PRSS2PRSS3TSHRMEN1
SCHEMBL28151612 0.82 LOXL2 (0.56) PRSS1PRSS2PRSS3TSHRENPP2
SCHEMBL814654 0.80 MEN1 (0.52) TSHRMEN1KMT2AMAPTHTT
SCHEMBL12802141 0.79 KAT6A (0.49) PRSS1PRSS2PRSS3CNR2MEN1
SCHEMBL21811989 0.78 MEN1 (0.50) TSHRMEN1KMT2AMAPTHTT
SCHEMBL28804284 0.78 F10 (0.43) MEN1KMT2ASMN1; SMN2NPC1TP53
SCHEMBL609571 0.78 ALDH1A1 (0.53) TSHRMEN1KMT2AGRM2
SCHEMBL16105770 0.78 FOLH1 (0.42) MEN1KMT2AFOLH1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4430097-B1 NEUTRAL BRUSHES WITH TUNABLE POLARITY FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS WITH POLY(STYRENE) AND POLY(METHYL METHACRYLATE) CONTAINING SEGMENTS MERCK PATENT GMBH (DE) 2026-04-01 EP disclosed
US-20250244671-A1 NEUTRAL BRUSHES WITH TUNABLE POLARITY FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS WITH POLY(STYRENE) AND POLY (METHYL METHACRYLATE) CONTAINING SEGMENTS EMD PERFORMANCE MATERIALS CORP. 2025-07-31 US disclosed
WO-2023083933-A1 NEUTRAL BRUSHES WITH TUNABLE POLARITY FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS WITH POLY(STYRENE) AND POLY(METHYL METHACRYLATE) CONTAINING SEGMENTS MERCK PATENT GMBH (DE) 2023-05-19 WO disclosed
CN-110114377-B Novel compositions and methods for block copolymer self-assembly 默克专利有限公司 2022-06-03 CN disclosed
EP-3858872-B1 COMPOSITIONS AND PROCESSES FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS MERCK PATENT GMBH (DE) 2022-05-11 EP disclosed
EP-3559053-B1 COMPOSITIONS AND PROCESSES FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS MERCK PATENT GMBH (DE) 2022-04-13 EP disclosed
EP-3858872-A1 NOVEL COMPOSITIONS AND PROCESSES FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS Merck Patent GmbH (DE) 2021-08-04 EP disclosed
US-11067893-B2 Compositions and processes for self-assembly of block copolymers MERCK PATENT GMBH (DE) 2021-07-20 US disclosed
EP-3559053-A1 NOVEL COMPOSITIONS AND PROCESSES FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS Ridgefield Acquisition (LU) 2019-10-30 EP disclosed
WO-2018114930-A1 NOVEL COMPOSITIONS AND PROCESSES FOR SELF-ASSEMBLY OF BLOCK COPOLYMERS AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2018-06-28 WO disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
CN-1735408-A Receptor function controlling agent TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2006-02-15 CN disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed
EP-0533695-B1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY PFIZER (US) 1994-10-05 EP disclosed
US-5322847-A Inhibit platelet activating factor, block leukotriene D4 receptors PFIZER INC. (US) 1994-06-21 US disclosed
EP-0533695-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. PFIZER (US) 1993-03-31 EP disclosed
WO-1991017163-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY PFIZER INC. (US) 1991-11-14 WO disclosed
US-4504491-A INSECTICIDE NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR PRSS1 2127/4885PRSS2 3290/4885PRSS3 3316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.