Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 10/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468913 | 0.91 | CYP19A1 (0.38) | LTA4H | |
| SCHEMBL17469006 | 0.89 | RIPK1 (0.35) | TAS1R3TAS1R1TAS1R2HDAC2NAMPT | |
| SCHEMBL17469012 | 0.86 | NAMPT (0.41) | NAMPTGSK3B | |
| SCHEMBL17468797 | 0.86 | LTA4H (0.33) | LTA4HNAMPTKMT2A | |
| SCHEMBL17469136 | 0.85 | SLC6A2 (0.32) | MEN1KMT2A | |
| SCHEMBL17468915 | 0.85 | LTA4H (0.31) | GUSBLTA4HGSK3B | |
| SCHEMBL17469009 | 0.85 | ABHD6 (0.34) | TAS1R3TAS1R1TAS1R2LTA4H | |
| SCHEMBL17469158 | 0.84 | GABRA1 (0.39) | MEN1KMT2A | |
| SCHEMBL17468801 | 0.84 | POLB (0.36) | TAS1R3TAS1R1TAS1R2HDAC2MEN1 | |
| SCHEMBL17469157 | 0.84 | MAOB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |