Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469008 | 0.91 | KIF11 (0.36) | RIPK1POLBKIF11FADS1AR | |
| SCHEMBL17469158 | 0.90 | GABRA1 (0.39) | HRH3ARMEN1KMT2AHCRTR2 | |
| SCHEMBL17459385 | 0.89 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2HDAC2NAMPT | |
| SCHEMBL17469007 | 0.85 | AR (0.38) | RIPK1POLBKIF11ARTAS1R3 | |
| SCHEMBL17469157 | 0.84 | MAOB (0.38) | RIPK1HCRTR2 | |
| SCHEMBL17468915 | 0.81 | LTA4H (0.31) | FADS1 | |
| SCHEMBL17468913 | 0.80 | CYP19A1 (0.38) | AR | |
| SCHEMBL17468916 | 0.79 | KIF11 (0.34) | KIF11 | |
| SCHEMBL17469150 | 0.78 | MGLL (0.35) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL17468801 | 0.78 | POLB (0.36) | POLBKIF11ARTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |