Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468913 | 0.88 | CYP19A1 (0.38) | ABHD6 | |
| SCHEMBL17459385 | 0.86 | TAS1R3 (0.38) | NAMPTGSK3B | |
| SCHEMBL17468797 | 0.84 | LTA4H (0.33) | NAMPTABHD6 | |
| SCHEMBL17469136 | 0.82 | SLC6A2 (0.32) | — | |
| SCHEMBL17468800 | 0.82 | ALDH1A1 (0.35) | NAMPTABHD6 | |
| SCHEMBL17468799 | 0.81 | ALDH1A1 (0.40) | NAMPT | |
| SCHEMBL17469002 | 0.80 | ABHD6 (0.36) | NAMPTSIRT2SIRT1ABHD6 | |
| SCHEMBL17469009 | 0.78 | ABHD6 (0.34) | ABHD6 | |
| SCHEMBL17468798 | 0.77 | TAS1R3 (0.38) | NAMPTABHD6 | |
| SCHEMBL17469160 | 0.77 | MGLL (0.35) | SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |