SCHEMBL17467282

SCHEMBL17467282

c1ccc(-c2cc(-c3ccc4c(c3)Cc3ccccc3-4)cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.46
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP2 O95551 2/20 0.44
MMP12 P39900 1/20 0.44
MMP13 P45452 1/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CNR1 P21554 1/20 0.41
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 1/20 0.39
PYGL P06737 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17467288 1.00 SRD5A2 (0.46) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL27389587 0.95 SRD5A2 (0.45) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL25945304 0.94 SRD5A2 (0.46) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL24608823 0.94 TDP2 (0.44) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL17467285 0.94 SRD5A2 (0.43) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL17467294 0.94 SRD5A2 (0.43) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL22068174 0.92 SRD5A2 (0.47) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL23919082 0.92 SRD5A2 (0.47) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL23255243 0.91 SRD5A2 (0.51) SRD5A2MAPTMEN1KMT2ATDP2
SCHEMBL25859172 0.91 SRD5A2 (0.51) SRD5A2MAPTMEN1KMT2ATDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818949-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-11641774-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-05-02 US disclosed
US-20230126221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20170054087-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-23 US disclosed
US-20170025618-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-01-26 US disclosed
US-20160093808-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-31 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 SRD5A2 306/4885MAPT 1163/4885MEN1 1828/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM SRD5A2 3901/4885MAPT 631/4885MEN1 452/4885
US-11818949-B2 Organic electroluminescent materials and devices EML4, TBCB, TERF2IP SRD5A2 3449/4885MAPT 814/4885MEN1 3089/4885
US-20170025618-A1 Organic Electroluminescent Materials and Devices TBCB, EML4, INMT SRD5A2 3328/4885MAPT 991/4885MEN1 3435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.