SCHEMBL17474259

SCHEMBL17474259

N#CC1(c2ccc(CCCCCCCCCCCc3ccc(C4(C#N)C=CC=CC4)cc3)cc2)C=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29257450 0.93 HSD17B10 (0.43) TSHRHSD17B10
SCHEMBL10725267 0.93 HSD17B10 (0.43) TSHRHSD17B10
SCHEMBL29084012 0.78 OPRM1 (0.38) OPRM1
SCHEMBL28484773 0.78 PGR (0.33) OPRM1TSHR
Benzene SCHEMBL28680468 0.77 OPRM1 (0.32) OPRM1
SCHEMBL27794540 0.77 OPRM1 (0.32) OPRM1
SCHEMBL29084028 0.74 ALDH1A1 (0.34)
SCHEMBL28366987 0.74 ALDH1A1 (0.41) OPRM1TSHR
SCHEMBL29796566 0.73 TSHR (0.40) TSHRHSD17B10
SCHEMBL29093603 0.72 MAPT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9690161-B2 Field induced heliconical structure of cholesteric liquid crystal KENT STATE UNIVERSITY (US) 2017-06-27 US claimed
US-20160033806-A1 FIELD INDUCED HELICONICAL STRUCTURE OF CHOLESTERIC LIQUID CRYSTAL KENT STATE UNIVERSITY 2016-02-04 US claimed
US-9732277-B2 Field induced and controlled heliconical structure of cholesteric liquid crystal KENT STATE UNIVERSITY (US) 2017-08-15 US disclosed
US-9690161-B2 Field induced heliconical structure of cholesteric liquid crystal KENT STATE UNIVERSITY (US) 2017-06-27 US disclosed
US-20160252755-A1 FIELD INDUCED AND CONTROLLED HELICONICAL STRUCTURE OF CHOLESTERIC LIQUID CRYSTAL KENT STATE UNIVERSITY 2016-09-01 US disclosed
US-20160033806-A1 FIELD INDUCED HELICONICAL STRUCTURE OF CHOLESTERIC LIQUID CRYSTAL KENT STATE UNIVERSITY 2016-02-04 US disclosed