Benzene

Benzene

SCHEMBL28680468

N#CC1(c2ccccc2)C=CC=CC1.c1ccccc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.32
CYP11B1 P15538 1/20 0.32
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27794540 1.00 OPRM1 (0.32) OPRM1CYP11B1CA12CA1CA2
SCHEMBL29084012 0.82 OPRM1 (0.38) OPRM1
SCHEMBL28484773 0.82 PGR (0.33) OPRM1CA12CA1CA2CA9
SCHEMBL30605440 0.81 HDAC4 (0.30) HDAC4
SCHEMBL29084130 0.80 HTR2C (0.33) OPRM1HDAC4
SCHEMBL29181879 0.80 SLC6A3 (0.35) CYP11B1
SCHEMBL29084028 0.78 ALDH1A1 (0.34)
SCHEMBL28366987 0.78 ALDH1A1 (0.41) OPRM1CA12CA1CA2CA9
SCHEMBL17474259 0.77 OPRM1 (0.33) OPRM1
SCHEMBL29181874 0.75 CYP11B1 (0.38) CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831491-A Preparation method and adsorption application of pyrimidazole covalent organic framework 南昌大学 2021-12-24 CN claimed
CN-113831491-A Preparation method and adsorption application of pyrimidazole covalent organic framework 南昌大学 2021-12-24 CN disclosed
CN-113831491-A Preparation method and adsorption application of pyrimidazole covalent organic framework 南昌大学 2021-12-24 CN disclosed