SCHEMBL28484773

SCHEMBL28484773

N#Cc1ccc(C2(C#N)C=CC=CC2)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.33
CA2 P00918 3/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2A6 P11509 1/20 0.32
CA12 O43570 1/20 0.32
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
POLB P06746 1/20 0.32
CA1 P00915 2/20 0.32
CYP19A1 P11511 2/20 0.31
TSHR P16473 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29084012 0.83 OPRM1 (0.38) ALDH1A1CYP2A6OPRM1
Benzene SCHEMBL28680468 0.82 OPRM1 (0.32) CA2CA12CA9CA1OPRM1
SCHEMBL27794540 0.82 OPRM1 (0.32) CA2CA12CA9CA1OPRM1
SCHEMBL28366987 0.79 ALDH1A1 (0.41) CA2ALDH1A1CA12CA9CA14
SCHEMBL29084028 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL17474259 0.78 OPRM1 (0.33) TSHROPRM1
SCHEMBL29093603 0.76 MAPT (0.34) PGRALDH1A1POLB
SCHEMBL29084104 0.76 MGAT2 (0.33)
SCHEMBL29084132 0.75 RAPGEF3 (0.33) ALDH1A1
SCHEMBL29181879 0.74 SLC6A3 (0.35) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108452821-B Pd/crystalline carbon nitride heterojunction photocatalyst, preparation method and application of photocatalytic Ullmann coupling reaction 陕西师范大学 2020-11-17 CN disclosed