SCHEMBL17483344

SCHEMBL17483344

CC1(C)c2ccccc2N(c2ccc(-c3c(C#N)c(C#N)c(-c4ccc(N5c6ccccc6C(C)(C)c6ccccc65)cc4)c(-c4ccccc4)c3-c3ccccc3)cc2)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 5/20 0.38
PGR P06401 1/20 0.38
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
PTPN1 P18031 2/20 0.36
GRIA2 P42262 3/20 0.36
AR P10275 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
FAAH O00519 1/20 0.34
MGLL Q99685 1/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ADRA2A P08913 1/20 0.33
ADORA2A P29274 1/20 0.33
PDE9A O76083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17483346 1.00 GRIA4 (0.38) GRIA4PGRALDH1A1KDM4ERXFP1
SCHEMBL17483390 0.97 PGR (0.39) GRIA4PGRALDH1A1KDM4ERXFP1
SCHEMBL17883172 0.93 PGR (0.40) GRIA4PGRALDH1A1KDM4ERXFP1
SCHEMBL17850986 0.88 GRIA4 (0.33) GRIA4PGRALDH1A1KDM4ERXFP1
SCHEMBL24432777 0.87 PDE9A (0.37) PGRALDH1A1KDM4ERXFP1MEN1
SCHEMBL23085274 0.86 KDM4E (0.31) GRIA4PGRALDH1A1KDM4EAR
SCHEMBL17850870 0.85 PGR (0.34) PGRARMEN1KMT2AHTT
SCHEMBL22417872 0.85 KDM4E (0.34) PGRALDH1A1KDM4ERXFP1AR
SCHEMBL19648909 0.84
SCHEMBL17483442 0.83 PGR (0.42) PGRALDH1A1KDM4EARMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2021-03-02 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
EP-3093326-B1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT, AND COMPOUND KYULUX INC (JP) 2020-03-18 EP disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2019-11-14 US disclosed
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2019-08-13 US disclosed
EP-2980877-B1 ORGANIC ELECTROLUMINESCENT ELEMENT KYULUX INC (JP) 2017-11-29 EP disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
EP-3093326-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT, AND COMPOUND Kyulux, Inc. (JP) 2016-11-16 EP disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-2980877-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 GRIA4 1153/4885PGR 735/4885ALDH1A1 2419/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 GRIA4 1153/4885PGR 735/4885ALDH1A1 2419/4885
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND CRY2, NR2E3, CRY1 GRIA4 378/4885PGR 1216/4885ALDH1A1 391/4885
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound CRY1, CRY2, GLB1 GRIA4 644/4885PGR 1378/4885ALDH1A1 307/4885
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound CRY2, NR2E3, CRY1 GRIA4 378/4885PGR 1216/4885ALDH1A1 391/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA GRIA4 1545/4885PGR 2538/4885ALDH1A1 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.