Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 4/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295089 | 0.84 | LPL (0.37) | PDGFRBKDRLPLLIPGDGAT1 | |
| SCHEMBL19295082 | 0.78 | DGAT1 (0.47) | PDGFRBKDRLPLLIPGDGAT1 | |
| SCHEMBL19300306 | 0.78 | DGAT1 (0.36) | PDGFRBKDRLPLLIPGDGAT1 | |
| SCHEMBL17486287 | 0.76 | CHRNA1 (0.34) | — | |
| SCHEMBL17486200 | 0.76 | DGAT1 (0.34) | PDGFRBKDRLPLLIPGDGAT1 | |
| SCHEMBL19295102 | 0.76 | IKBKB (0.34) | DGAT1 | |
| SCHEMBL17486295 | 0.74 | LPL (0.32) | LPLLIPG | |
| SCHEMBL2427133 | 0.73 | ESR2 (0.38) | LPLLIPG | |
| SCHEMBL19794326 | 0.73 | DGAT1 (0.49) | PDGFRBKDRLPLLIPGDGAT1 | |
| SCHEMBL15614879 | 0.73 | LIPG (0.41) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174890-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170250353-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | PDGFRB 4861/4885KDR 4513/4885LPL 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.