Bromide

Bromide

SCHEMBL17501903

NCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.56
HRH1 P35367 2/20 0.47
HTR2A P28223 1/20 0.47
CHRNA7 P36544 8/20 0.45
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAOA P21397 1/20 0.43
TRAP1 Q12931 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL22265893 1.00 HIF1A (0.56) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL20541910 1.00 HIF1A (0.56) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL4207555 1.00 HIF1A (0.56) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL20541311 1.00 HIF1A (0.56) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL18729719 1.00 HIF1A (0.56) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL20541756 1.00 HIF1A (0.56) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL23883184 0.98 HIF1A (0.54) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL2552372 0.98 HIF1A (0.54) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Bromide SCHEMBL2552373 0.98 HIF1A (0.54) HIF1AHRH1HTR2ACHRNA7ALDH1A1
Hydrochloric Acid SCHEMBL30872528 0.98 HIF1A (0.54) HIF1AHRH1HTR2ACHRNA7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035504-A1 POLYMER AND USE THEREOF SHENZHEN SENIOR TECHNOLOGY MATERIAL CO LTD (CN) 2026-02-05 US disclosed
EP-4626900-A1 PORPHYRIN AND PHOSPHONIUM-PORPHYRIN BASED COMPOUNDS FOR PHOTODYNAMIC THERAPY AND DIAGNOSTICS RMW Cho Group Limited (HK) 2025-10-08 EP disclosed
US-20250177533-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS Invion Limited (AU) 2025-06-05 US disclosed
US-20250115633-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS Invion Limited (AU) 2025-04-10 US disclosed
EP-4436972-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW Cho Group Limited (HK) 2024-10-02 EP disclosed
EP-4436971-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW Cho Group Limited (HK) 2024-10-02 EP disclosed
CN-118679165-A Photodynamic therapy and diagnosis RMW曹氏集团有限公司 2024-09-20 CN disclosed
CN-118679164-A Photodynamic therapy and diagnosis RMW曹氏集团有限公司 2024-09-20 CN disclosed
WO-2024115524-A1 PORPHYRIN AND PHOSPHONIUM-PORPHYRIN BASED COMPOUNDS FOR PHOTODYNAMIC THERAPY AND DIAGNOSTICS RMW CHO GROUP LIMITED (CN) 2024-06-06 WO disclosed
WO-2023094679-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS RMW CHO GROUP LIMITED (CN) 2023-06-01 WO disclosed
US-20190091245-A1 Neuroprotection by mitochondria-targeted metformin NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-03-28 US disclosed
WO-2018193116-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS NOVINTUM BIOTECHNOLOGY GMBH (CH) 2018-10-25 WO disclosed
WO-2018193126-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTIBACTERIAL AGENTS NOVINTUM BIOTECHNOLOGY GMBH (CH) 2018-10-25 WO disclosed
WO-2018193117-A1 AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS NOVINTUM BIOTECHNOLOGY GMBH (CH) 2018-10-25 WO disclosed
WO-2018119207-A1 SYNERGISTIC INIHIBITION OF TUMOR CELL PROLIFERATION INDUCED BY COMBINED TREATMENT OF METFORMIN COMPOUNDS AND IRON CHELATORS THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) 2018-06-28 WO disclosed
US-9956233-B2 Neuroprotection by mitochondria-targeted metformin IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2018-05-01 US disclosed
US-20170275313-A1 MODIFIED MITO-METFORMIN COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF THE MEDICAL COLLEGE OF WISCONSIN, INC. 2017-09-28 US disclosed
EP-3179994-A1 MODIFIED MITO-METFORMIN COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF The Medical College of Wisconsin, Inc. (US) 2017-06-21 EP disclosed
US-20170106006-A1 Neuroprotection by Mitochondria-Targeted Metformin AIX-MARSEILLE UNIVERSITE (FR) 2017-04-20 US disclosed
WO-2016025725-A1 MODIFIED MITO-METFORMIN COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) 2016-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170275313-A1 MODIFIED MITO-METFORMIN COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF TFAM, MFN2, MT-ND5 HIF1A 828/4885HRH1 4791/4885HTR2A 2753/4885
US-20250115633-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS TPD52L2, CPNE4, CCNE2 HIF1A 1063/4885HRH1 2705/4885HTR2A 3764/4885
US-20170106006-A1 Neuroprotection by Mitochondria-Targeted Metformin NLN, MFN2, TFAM HIF1A 380/4885HRH1 4569/4885HTR2A 983/4885
US-20260035504-A1 POLYMER AND USE THEREOF CCNT1, C1S, CCNA1 HIF1A 1833/4885HRH1 3887/4885HTR2A 4455/4885
US-20250177533-A1 PHOTODYNAMIC THERAPY AND DIAGNOSIS PPOX, PPIF, ALAD HIF1A 700/4885HRH1 4025/4885HTR2A 3831/4885
US-20190091245-A1 Neuroprotection by mitochondria-targeted metformin NLN, MFN2, TFAM HIF1A 380/4885HRH1 4569/4885HTR2A 983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.