Fraxinellone

Fraxinellone

SCHEMBL17503653

CC1=C2C(=O)O[C@@H](c3ccoc3)[C@]2(C)CCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 1.00
▸ TSHR P16473 1/20 1.00
▸ CYP3A4 P08684 11/20 0.39
▸ SLCO1B3 Q9NPD5 6/20 0.39
▸ SLCO1B1 Q9Y6L6 6/20 0.39
▸ TP53 P04637 4/20 0.39
▸ SULT1E1 P49888 1/20 0.37
▸ USP2 O75604 6/20 0.35
▸ SMN1; SMN2 Q16637 4/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 3/20 0.34
▸ FFAR3 O14843 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fraxinellone SCHEMBL17503654 1.00 GAA (1.00) GAATSHRCYP3A4SLCO1B3SLCO1B1
Fraxinellone SCHEMBL25272092 1.00 GAA (1.00) GAATSHRCYP3A4SLCO1B3SLCO1B1
SCHEMBL30008897 0.84 GAA (0.72) GAATSHRSULT1E1ALDH1A1
Fraxinellonone SCHEMBL29065291 0.82 GAA (0.70) GAATSHRCYP3A4SLCO1B3SLCO1B1
4Alpha-Hydroxyfraxinellone SCHEMBL30697308 0.80 GAA (0.66) GAATSHRCYP3A4SLCO1B3SLCO1B1
4Alpha-Hydroxyfraxinellone SCHEMBL30150287 0.80 GAA (0.66) GAATSHRCYP3A4SLCO1B3SLCO1B1
SCHEMBL30150288 0.79 GAA (0.65) GAATSHRCYP3A4SLCO1B3SLCO1B1
SCHEMBL30574475 0.62 GAA (0.46) GAATSHRCYP3A4SLCO1B3SLCO1B1
SCHEMBL19590566 0.62 GAA (0.45) GAATSHRCYP3A4SLCO1B3SLCO1B1
SCHEMBL30150305 0.61 GAA (0.44) GAATSHRCYP3A4SLCO1B3SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023117768-A1 COMBINATION OF DRUGS FOR THE TREATMENT OF CANCER SCANDION ONCOLOGY A/S (DK) 2023-06-29 — — WO claimed
EP-4197525-A1 COMBINATION OF DRUGS FOR THE TREATMENT OF CANCER Scandion Oncology A/S (DK) 2023-06-21 — — EP claimed
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 — — US disclosed
EP-4691496-A1 PHARMACEUTICAL PREPARATION CONTAINING GLP-1 FUSION PROTEIN AND USE THEREOF Guangzhou Innogen Pharmaceutical Group Co., Ltd. (CN) 2026-02-11 — — EP disclosed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 — — US disclosed
US-20250376498-A1 FUSION PROTEINS COMPRISING AN IMPROVED GLP-1 RECEPTOR AGONIST AND USES THEREOF GUANGZHOU INNOGEN PHARMACEUTICAL GROUP CO LTD (CN) 2025-12-11 — — US disclosed
EP-3995586-B1 GLYCOSYLATED PROTEIN ASSAY REAGENT CONTAINING PROTEASE STABILIZER INCREASING REDOX POTENTIAL OF FERROCYANIDE, METHOD FOR ASSAYING GLYCOSYLATED PROTEIN, METHOD FOR PRESERVING GLYCOSYLATED PROTEIN ASSAY REAGENT, AND METHOD FOR STABILIZING GLYCOSYLATED PROTEIN ASSAY REAGENT NAGASE DIAGNOSTICS CO LTD (JP) 2025-11-05 — — EP disclosed
CN-114267421-B Extraction process for optimizing three effective components of cortex dictamni by combining analytic hierarchy process with response surface method 吉林化工学院 2025-05-23 — — CN disclosed
EP-4545570-A1 FUSION PROTEIN CONTAINING IMPROVED GLP-1 RECEPTOR AGONIST AND USES Guangzhou Innogen Pharmaceutical Group Co., Ltd. (CN) 2025-04-30 — — EP disclosed
US-20240238295-A1 METHOD FOR MODULATING NEUROPATHIES CHENGDU WENDING TECHNOLOGY DEVELOPMENT CO., LTD (CN) 2024-07-18 — — US disclosed
US-20240178398-A1 WATER BASED BINDER COMPOSITION AND APPLICATION THEREOF ARKEMA INC. 2024-05-30 — — US disclosed
EP-2976457-B1 TEXTILE PRODUCTS WITH HERBAL COMPOSITION TO RENDER THE FABRICS INSECTS REPELLENT SYNTIS TEXTILE PRIVATE LTD (IN) 2019-08-07 — — EP disclosed
US-9816227-B2 Textile products with herbal composition to render the fabrics insects repellent SYNTIS TEXTILE PRIVATE LTD (IN) 2017-11-14 — — US disclosed
US-9816227-B2 Textile products with herbal composition to render the fabrics insects repellent SYNTIS TEXTILE PRIVATE LTD (IN) 2017-11-14 — — US disclosed
US-9816227-B2 Textile products with herbal composition to render the fabrics insects repellent SYNTIS TEXTILE PRIVATE LTD (IN) 2017-11-14 — — US disclosed
US-20160047086-A1 TEXTILE PRODUCTS WITH HERBAL COMPOSITION TO RENDER THE FABRICS INSECTS REPELLENT SYNTIS TEXTILE PRIVATE LTD (IN) 2016-02-18 — — US disclosed
US-20160047086-A1 TEXTILE PRODUCTS WITH HERBAL COMPOSITION TO RENDER THE FABRICS INSECTS REPELLENT SYNTIS TEXTILE PRIVATE LTD (IN) 2016-02-18 — — US disclosed
US-20160047086-A1 TEXTILE PRODUCTS WITH HERBAL COMPOSITION TO RENDER THE FABRICS INSECTS REPELLENT SYNTIS TEXTILE PRIVATE LTD (IN) 2016-02-18 — — US disclosed
CN-101618106-B Pharmaceutical composition for curing psoriasis JILIN CAOHUANDAN PHARMACEUTICAL CO LTD 2012-02-29 — — CN disclosed
CN-101618106-A Pharmaceutical composition for curing psoriasis JILIN CAOHUANDAN PHARMACEUTICA 2010-01-06 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250376498-A1 FUSION PROTEINS COMPRISING AN IMPROVED GLP-1 RECEPTOR AGONIST AND USES THEREOF GLP1R, GIPR, GCGR GAA 864/4885TSHR 166/4885CYP3A4 4606/4885
US-20160047086-A1 TEXTILE PRODUCTS WITH HERBAL COMPOSITION TO RENDER THE FABRICS INSECTS REPELLENT CRY1, TREH, TMSB10 GAA 2280/4885TSHR 1790/4885CYP3A4 583/4885
US-20240238295-A1 METHOD FOR MODULATING NEUROPATHIES MME, PMP22, NEFM GAA 1205/4885TSHR 2533/4885CYP3A4 1596/4885
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION COL2A1, COLGALT1, PLOD3 GAA 1518/4885TSHR 4804/4885CYP3A4 3867/4885
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME SQSTM1, BECN1, CUTA GAA 931/4885TSHR 4819/4885CYP3A4 4670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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