Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17505172 | 0.84 | KMT2A (0.41) | GPR84HSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL17505165 | 0.82 | GPR84 (0.37) | GPR84BACE1HSD17B10ALDH1A1HPGD | |
| SCHEMBL17505183 | 0.73 | KDM4E (0.50) | HSD17B10ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL22185228 | 0.71 | HRH4 (0.43) | HSD17B10ALDH1A1KDM4E | |
| SCHEMBL21549811 | 0.70 | KDM4E (0.40) | HSD17B10ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL12967907 | 0.69 | CYP2A6 (0.46) | ALDH1A1TSHR | |
| SCHEMBL12184907 | 0.67 | TAAR1 (0.42) | GPR84HSD17B10ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL17505178 | 0.67 | KDM4E (0.61) | HSD17B10ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL18744798 | 0.67 | HRH4 (0.40) | HSD17B10ALDH1A1KDM4E | |
| SCHEMBL17505139 | 0.65 | ALDH1A1 (0.43) | HSD17B10ALDH1A1HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |