Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17493468 | 0.79 | CA2 (0.43) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL182738 | 0.72 | LMNA (0.67) | HTR6PSIP1LMNAAPOBEC3GHSD11B1 | |
| Water SCHEMBL28154432 | 0.70 | LMNA (0.64) | HTR6LMNAAPOBEC3GHSD11B1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1017218 | 0.70 | LMNA (0.64) | HTR6LMNAAPOBEC3GHSD11B1ALDH1A1 | |
| SCHEMBL2178308 | 0.70 | HTR6 (0.48) | HTR6PSIP1LMNAAPOBEC3GALDH1A1 | |
| SCHEMBL2178473 | 0.70 | HTR6 (0.48) | HTR6PSIP1LMNAAPOBEC3GALDH1A1 | |
| Hydrochloric Acid SCHEMBL19211700 | 0.70 | LMNA (0.64) | HTR6LMNAAPOBEC3GHSD11B1ALDH1A1 | |
| SCHEMBL486788 | 0.70 | HTR6 (0.48) | HTR6PSIP1LMNAAPOBEC3GALDH1A1 | |
| SCHEMBL10363486 | 0.68 | CA1 (0.54) | HTR6PSIP1LMNAALDH1A1HSD17B10 | |
| SCHEMBL11679652 | 0.68 | HTR6 (0.46) | HTR6PSIP1LMNAAPOBEC3GHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180338-A1 | AZABENZIMIDAZOLE DERIVATIVES AS AMP PROTEIN KINASE AGONISTES | Boehringer Ingelheim International GmbH (DE) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016023789-A1 | AZABENZIMIDAZOLE DERIVATIVES AS AMP PROTEIN KINASE AGONISTES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-18 | — | — | WO | disclosed |