Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486788 | 0.73 | HTR6 (0.48) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL2178473 | 0.73 | HTR6 (0.48) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL2178308 | 0.73 | HTR6 (0.48) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL10363486 | 0.71 | CA1 (0.54) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL514197 | 0.71 | HTR6 (0.58) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL474153 | 0.70 | ALDH1A1 (0.52) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL18402598 | 0.68 | KDM4E (0.43) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL17509193 | 0.68 | HTR6 (0.42) | HTR6PSIP1HSD11B1ALDH1A1CA1 | |
| Methylphenylsulfone SCHEMBL28158010 | 0.67 | PTGS2 (0.58) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL8320274 | 0.67 | HTR6 (0.52) | HTR6PSIP1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060534-A | 9-Deoxy-9-methylene-PGF compounds | THE UPJOHN COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4021467-A | 9-Deoxy-9α-hydroxymethyl-PGF2 analogs | THE UPJOHN COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
| US-3950363-A | PROSTAGLANDIN CYCLIC ETHERS | THE UPJOHN COMPANY (US) | 1976-04-13 | — | — | US | disclosed |