Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 6/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513922 | 0.80 | NPC1 (0.38) | RAB9ANPC1GPR52ALDH1A1KDM4E | |
| SCHEMBL17513997 | 0.80 | GRM5 (0.41) | RAB9ANPC1GPR52GRM5ALDH1A1 | |
| SCHEMBL17513904 | 0.78 | GPR52 (0.43) | RAB9ANPC1GPR52ALDH1A1KDM4E | |
| SCHEMBL17513938 | 0.77 | CA12 (0.39) | RAB9ANPC1GPR52ALDH1A1MAPT | |
| SCHEMBL17514012 | 0.76 | FFAR1 (0.37) | RAB9ANPC1GPR52ALDH1A1MAPK1 | |
| SCHEMBL17513952 | 0.73 | NPC1 (0.46) | RAB9ANPC1ALDH1A1HTTMAPT | |
| SCHEMBL17513894 | 0.73 | ALOX5 (0.36) | RAB9ANPC1GPR52ALDH1A1TSHR | |
| SCHEMBL17632072 | 0.72 | NPC1 (0.48) | RAB9ANPC1GRM5ALDH1A1MAPK1 | |
| SCHEMBL17514014 | 0.71 | ATM (0.53) | RAB9ANPC1ALDH1A1MAPTTSHR | |
| SCHEMBL17513966 | 0.71 | GRM5 (0.43) | RAB9ANPC1GRM5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197482-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| EP-3182992-A1 | METHODS OF TREATING MILD BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016048488-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016028826-A1 | METHODS OF TREATING MILD BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-02-25 | — | — | WO | disclosed |