SCHEMBL17514751

SCHEMBL17514751

COc1[c]cccc1-c1cc(F)ccc1Br

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.32
S1PR1 P21453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514690 0.88 AMY1A (0.34) AMY1AS1PR1
SCHEMBL17514527 0.84 PTPN1 (0.36)
SCHEMBL17514960 0.83 HTR7 (0.35) S1PR1
SCHEMBL17514995 0.82 HTR1A (0.37) AMY1A
SCHEMBL17514930 0.81 MAPK14 (0.37) AMY1A
SCHEMBL17514951 0.80 S1PR1 (0.38) S1PR1
SCHEMBL17514655 0.79 HSD11B1 (0.41) AMY1A
SCHEMBL17515015 0.78 MAOB (0.34)
SCHEMBL6985969 0.76 SLC6A4 (0.42)
SCHEMBL16719652 0.75 TUBB4A (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed