SCHEMBL1751797

SCHEMBL1751797

COC(=O)Cc1ccc(O)c(OC)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.73
ALDH1A1 P00352 2/20 0.73
TSHR P16473 2/20 0.73
NFKB1 P19838 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
GFER P55789 1/20 0.66
ALOX5 P09917 1/20 0.62
OR51E2 Q9H255 1/20 0.62
TAAR1 Q96RJ0 2/20 0.57
MAPK1 P28482 1/20 0.57
MTNR1A P48039 1/20 0.56
MTNR1B P49286 1/20 0.56
FOS P01100 1/20 0.56
TTR P02766 1/20 0.56
JUN P05412 1/20 0.56
NR3C1 P04150 1/20 0.56
HSD17B1 P14061 1/20 0.56
HSD17B2 P37059 1/20 0.56
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30128009 1.00 GAA (0.73) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL9040078 0.90 TSHR (0.73) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL5536197 0.87 ALDH1A1 (0.56) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL13262269 0.86 MAPT (0.59) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL1011093 0.86 GAA (0.73) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL198282 0.86 ALDH1A1 (0.62) GAAALDH1A1GFERMAPK1LMNA
SCHEMBL7114863 0.86 TSHR (0.77) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL29626821 0.86 ALDH1A1 (0.62) GAAALDH1A1GFERMAPK1LMNA
SCHEMBL2002022 0.85 ALDH1A1 (0.67) GAAALDH1A1TSHRNFKB1TDP1
SCHEMBL30038050 0.85 ALDH1A1 (0.67) GAAALDH1A1TSHRNFKB1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250384-A1 BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS UNIVERSITY OF DELAWARE 2025-08-07 US claimed
US-20230113164-A1 BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS UNIVERSITY OF DELAWARE (US) 2023-04-13 US claimed
CN-115697961-A Preparation method of high-fragrance oxalate 西姆莱斯有限公司 2023-02-03 CN claimed
US-11525024-B2 Bio-based polymers from raw lignocellulosic biomass UNIVERSITY OF DELAWARE (US) 2022-12-13 US claimed
US-20190144590-A1 BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS UNIVERSITY OF DELAWARE (US) 2019-05-16 US claimed
EP-4680210-A1 MEDICAL PATCH COMPRISING SKIN IRRITATING ACTIVE AGENT LTS Lohmann Therapie-Systeme AG (DE) 2026-01-21 EP disclosed
US-20250297321-A1 METHOD FOR DETECTING METABOLIC REPROGRAMING OF CANCER TOWARDS FATTY ACIDS METABOLISM INST NAT SANTE RECH MED (FR) 2025-09-25 US disclosed
US-20250250384-A1 BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS UNIVERSITY OF DELAWARE 2025-08-07 US disclosed
US-12291592-B2 Ion-conducting bio-based polymers from raw lignocellulosic biomass UNIVERSITY OF DELAWARE (US) 2025-05-06 US disclosed
WO-2024189213-A1 MEDICAL PATCH COMPRISING SKIN IRRITATING ACTIVE AGENT LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2024-09-19 WO disclosed
US-RE49934-E1 Inhibitors of cellular metabolic processes SERVIER PHARMACEUTICALS LLC (US) 2024-04-23 US disclosed
CN-116535304-A Erianin analogue, and synthetic method and application thereof 中国科学院成都生物研究所 2023-08-04 CN disclosed
WO-2001000603-A1 THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE GLAXO GROUP LIMITED (GB) 2001-01-04 WO disclosed
US-6090836-A DIETETICS; ADJUSTMENT OF TRIGLYCERIDE CONCENTRATION MERCK & CO., INC. (US) 2000-07-18 US disclosed
EP-0882029-A1 HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS Merck & Co., Inc. (US) 1998-12-09 EP disclosed
WO-1997028137-A1 HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS MERCK & CO., INC. (US) 1997-08-07 WO disclosed
EP-0315399-B1 Quinoline derivatives, their use in the treatment of hypersensitive ailments and a pharmaceutical composition containing the same RHONE POULENC RORER INT (US) 1996-01-10 EP disclosed
US-5304563-A Lipoxygenase inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1994-04-19 US disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12291592-B2 Ion-conducting bio-based polymers from raw lignocellulosic biomass ME1, FHIT, BOLA2; BOLA2B GAA 1447/4885ALDH1A1 317/4885TSHR 4833/4885
US-20250250384-A1 BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS ME1, BLVRB, FHIT GAA 867/4885ALDH1A1 224/4885TSHR 4858/4885
US-20230113164-A1 BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS ME1, BLVRB, FHIT GAA 871/4885ALDH1A1 333/4885TSHR 4845/4885
US-11525024-B2 Bio-based polymers from raw lignocellulosic biomass ME1, BLVRB, PLOD1 GAA 1462/4885ALDH1A1 280/4885TSHR 4884/4885
US-20190144590-A1 BIO-BASED POLYMERS FROM RAW LIGNOCELLULOSIC BIOMASS ME1, BLVRB, PLOD1 GAA 1462/4885ALDH1A1 280/4885TSHR 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.