Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557086 | 1.00 | NAAA (0.57) | NAAANPC1LMNATP53HPGD | |
| SCHEMBL19281759 | 1.00 | NAAA (0.57) | NAAANPC1LMNATP53HPGD | |
| SCHEMBL14541033 | 0.88 | ALDH1A1 (0.53) | NAAANPC1LMNATP53RAB9A | |
| SCHEMBL20902214 | 0.88 | NAAA (0.46) | NAAANPC1LMNATP53HPGD | |
| SCHEMBL18007116 | 0.87 | NAAA (0.57) | NAAANPC1LMNATP53HPGD | |
| SCHEMBL19810282 | 0.87 | NAAA (0.57) | NAAANPC1LMNATP53HPGD | |
| SCHEMBL31354985 | 0.86 | HPGD (0.50) | NAAANPC1LMNATP53HPGD | |
| SCHEMBL23327035 | 0.85 | CASP3 (0.48) | NAAALMNARAB9AALDH1A1HTT | |
| SCHEMBL23327036 | 0.85 | CASP3 (0.48) | NAAALMNARAB9AALDH1A1HTT | |
| SCHEMBL13340721 | 0.85 | NAAA (0.49) | NAAANPC1LMNATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093625-B2 | Process for the preparation of [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid dihydrate | MSN LABORATORIES PRIVATE LIMITED (IN) | 2018-10-09 | — | — | US | claimed |
| US-20170247328-A1 | IMPROVED PROCESS FOR THE PREPARATION OF [[2(S)-[[4(R)-(3-HYDROXYPHENYL)-3(R),4-DIMETHYL-1-PIPERIDINYL]METHYL]-1-OXO-3-PHENYLPROPYL]AMINO]ACETIC ACID DIHYDRATE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2017-08-31 | — | — | US | claimed |
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2020-06-02 | — | — | US | disclosed |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2019-02-07 | — | — | US | disclosed |
| US-10093625-B2 | Process for the preparation of [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid dihydrate | MSN LABORATORIES PRIVATE LIMITED (IN) | 2018-10-09 | — | — | US | disclosed |
| US-10040812-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2018-08-07 | — | — | US | disclosed |
| US-10040812-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2018-08-07 | — | — | US | disclosed |
| US-20170247328-A1 | IMPROVED PROCESS FOR THE PREPARATION OF [[2(S)-[[4(R)-(3-HYDROXYPHENYL)-3(R),4-DIMETHYL-1-PIPERIDINYL]METHYL]-1-OXO-3-PHENYLPROPYL]AMINO]ACETIC ACID DIHYDRATE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2017-08-31 | — | — | US | disclosed |
| US-20170247328-A1 | IMPROVED PROCESS FOR THE PREPARATION OF [[2(S)-[[4(R)-(3-HYDROXYPHENYL)-3(R),4-DIMETHYL-1-PIPERIDINYL]METHYL]-1-OXO-3-PHENYLPROPYL]AMINO]ACETIC ACID DIHYDRATE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2017-08-31 | — | — | US | disclosed |
| US-20170247328-A1 | IMPROVED PROCESS FOR THE PREPARATION OF [[2(S)-[[4(R)-(3-HYDROXYPHENYL)-3(R),4-DIMETHYL-1-PIPERIDINYL]METHYL]-1-OXO-3-PHENYLPROPYL]AMINO]ACETIC ACID DIHYDRATE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2017-08-31 | — | — | US | disclosed |
| US-20170233420-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2017-08-17 | — | — | US | disclosed |
| US-20170233420-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2017-08-17 | — | — | US | disclosed |
| WO-2016019475-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233420-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | TPO, CYP4F2, FANCF | NAAA 1130/4885NPC1 2516/4885LMNA 4834/4885 |
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | TPO, FANCF, FANCI | NAAA 3222/4885NPC1 2420/4885LMNA 4363/4885 |
| US-20170247328-A1 | IMPROVED PROCESS FOR THE PREPARATION OF [[2(S)-[[4(R)-(3-HYDROXYPHENYL)-3(R),4-DIMETHYL-1-PIPERIDINYL]METHYL]-1-OXO-3-PHENYLPROPYL]AMINO]ACETIC ACID DIHYDRATE | HPD, GRHPR, HCAR2 | NAAA 681/4885NPC1 4545/4885LMNA 4313/4885 |
| US-10093625-B2 | Process for the preparation of [[2(S)-[[4(R)-(3-hydroxyphenyl)-3(R),4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid dihydrate | HPD, HCAR2, GRHPR | NAAA 744/4885NPC1 4530/4885LMNA 4189/4885 |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | TPO, FANCF, FANCI | NAAA 3222/4885NPC1 2420/4885LMNA 4363/4885 |
| US-10040812-B2 | Hypervalent iodine CF2CF2X reagents and their use | TPO, CYP4F2, FANCF | NAAA 1130/4885NPC1 2516/4885LMNA 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.