SCHEMBL17525567

SCHEMBL17525567

Cn1cncc1CCN1C(=O)CCCC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
CHRM5 P08912 3/20 0.41
LMNA P02545 3/20 0.40
CYP3A4 P08684 3/20 0.40
CHRM4 P08173 2/20 0.40
CHRM1 P11229 2/20 0.40
CYP2C9 P11712 2/20 0.40
CHRM3 P20309 2/20 0.40
CHRM2 P08172 1/20 0.40
CYP2A6 P11509 1/20 0.40
CNR1 P21554 1/20 0.40
HTR2A P28223 1/20 0.40
CYP2A13 Q16696 1/20 0.40
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10425365 0.74 CHRM5 (0.43) MEN1KMT2ACHRM5LMNACYP3A4
SCHEMBL6966596 0.73 MAPT (0.50) MAPT
SCHEMBL2328317 0.73 PIK3CD (0.41) KMT2ACHRM5MAPK1
SCHEMBL17525770 0.72 MEN1 (0.44) MEN1KMT2APOLBCYP3A4USP2
SCHEMBL17525761 0.71 CA1 (0.41) MEN1KMT2APOLBCYP3A4CYP2C9
SCHEMBL9570214 0.71
SCHEMBL4301227 0.70 TBXAS1 (0.44) MEN1KMT2ACHRM5LMNACYP3A4
SCHEMBL4300091 0.69
SCHEMBL17525782 0.69 HRH3 (0.50) LMNA
SCHEMBL2171709 0.68 CHRM5 (0.37) MEN1KMT2ACHRM5LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3722290-B1 GLUTARIMIDE DERIVATIVE, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING THE GLUTARIMIDE DERIVATIVE VALENTA INTELLEKT LTD (RU) 2023-06-21 EP disclosed
EP-3725785-A1 GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) 2020-10-21 EP disclosed
EP-3722290-A1 GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) 2020-10-14 EP disclosed
US-10377739-B2 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) 2019-08-13 US disclosed
US-20190084961-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2019-03-21 US disclosed
US-10196377-B2 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) 2019-02-05 US disclosed
US-20180022728-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-25 US disclosed
US-20180022728-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-25 US disclosed
US-20180016255-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016254-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016255-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016254-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016257-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016253-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016256-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016256-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-20180016253-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) 2018-01-18 US disclosed
US-9815814-B2 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) 2017-11-14 US disclosed
US-9815814-B2 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) 2017-11-14 US disclosed
EP-2985282-A1 GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING GLUTARIMIDE DERIVATIVES Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) 2016-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10377739-B2 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives GCDH, GLS, HADH MEN1 1963/4885KMT2A 2520/4885POLB 2372/4885
US-20180022728-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives GCDH, GLS, HADH MEN1 2009/4885KMT2A 2594/4885POLB 2180/4885
US-20180016256-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives GCDH, GOT2, GLS MEN1 2348/4885KMT2A 2402/4885POLB 2322/4885
US-10196377-B2 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives GCDH, GLS, HADH MEN1 1963/4885KMT2A 2520/4885POLB 2372/4885
US-20180016255-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives GCDH, NOTUM, CYP11B2 MEN1 3780/4885KMT2A 2144/4885POLB 2923/4885
US-20190084961-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives GCDH, GLS, HADH MEN1 1963/4885KMT2A 2520/4885POLB 2372/4885
US-20180016254-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives GCDH, HADH, GOT2 MEN1 2112/4885KMT2A 2526/4885POLB 2370/4885
US-20180016253-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives GCDH, GLS, HADH MEN1 2123/4885KMT2A 2797/4885POLB 2758/4885
US-20180016257-A1 Glutarimide Derivatives, Use Thereof, Pharmaceutical Composition Based Thereon and Methods for Producing Glutarimide Derivatives GCDH, HADH, OGDH MEN1 1324/4885KMT2A 2208/4885POLB 2275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.