Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732597 | 0.83 | CYP2A6 (0.42) | CYP2A6TGFBR1RIPK2HPGDSALKBH2 | |
| SCHEMBL2730846 | 0.81 | HTT (0.48) | CYP2A6TGFBR1RIPK2HPGDSALKBH2 | |
| SCHEMBL28810506 | 0.80 | TGFBR1 (0.43) | CYP2A6TGFBR1RIPK2HPGDSALKBH2 | |
| SCHEMBL15975572 | 0.80 | CYP2A6 (0.39) | CYP2A6TGFBR1RIPK2HPGDSALKBH2 | |
| SCHEMBL17535300 | 0.79 | ELOVL1 (0.36) | RIPK2 | |
| SCHEMBL17802489 | 0.78 | ADORA3 (0.42) | NAMPTADORA3MAPK1MAPK13MAPK12 | |
| SCHEMBL10235989 | 0.78 | GPR119 (0.43) | CYP2A6TGFBR1RIPK2HPGDSALKBH2 | |
| SCHEMBL4965578 | 0.77 | CYP2A6 (0.42) | CYP2A6TGFBR1RIPK2HPGDSALKBH2 | |
| SCHEMBL4066046 | 0.77 | HTT (0.44) | NAMPTGAA | |
| SCHEMBL2690352 | 0.77 | GPR119 (0.42) | CYP2A6TGFBR1RIPK2MTORERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160159766-A9 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-06-09 | — | — | US | disclosed |
| US-9282739-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-03-15 | — | — | US | disclosed |
| US-20160060245-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159766-A9 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885TGFBR1 1799/4885RIPK2 2576/4885 |
| US-20160060245-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885TGFBR1 1799/4885RIPK2 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.