Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536329 | 0.82 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL16041491 | 0.72 | GABRA1 (0.41) | ALDH1A1LMNAHTTSIGMAR1GABRA1 | |
| SCHEMBL11869540 | 0.71 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL11760747 | 0.70 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL11869498 | 0.70 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL17536328 | 0.70 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL17536308 | 0.69 | HCRTR1 (0.38) | ALDH1A1SMN1; SMN2TP53LMNANPC1 | |
| SCHEMBL6616831 | 0.67 | ALOX5 (0.40) | LMNAKMT2ASIGMAR1GABRA1GABRB2 | |
| SCHEMBL20267556 | 0.67 | SIGMAR1 (0.34) | ALDH1A1LMNAKMT2ASIGMAR1GABRA1 | |
| SCHEMBL24502787 | 0.66 | KMT2A (0.36) | SMN1; SMN2LMNAKMT2ASIGMAR1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3185685-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | Dow AgroSciences LLC (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9469617-B2 | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-10-18 | — | — | US | disclosed |
| US-20160060233-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-03-03 | — | — | US | disclosed |
| WO-2016033025-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060233-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | ALDH1A1 238/4885SMN1; SMN2 3702/4885TP53 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.