Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 4/20 | 0.35 |
| ▸ | GABRD | O14764 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.35 |
| ▸ | GABRE | P78334 | 4/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874438 | 0.78 | LMNA (0.47) | POLBLMNAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL15848600 | 0.73 | GABRD (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22136186 | 0.72 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17544295 | 0.71 | GRIN1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22136187 | 0.71 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15352511 | 0.70 | GABRP (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17544857 | 0.70 | HSD11B1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11617892 | 0.69 | GABRP (0.31) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14837737 | 0.69 | GRIN1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30518139 | 0.69 | GRIN1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186267-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016029888-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2016-03-03 | — | — | WO | disclosed |