Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.43 |
| ▸ | GABRD | O14764 | 7/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.39 |
| ▸ | GABRP | O00591 | 6/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.39 |
| ▸ | GABRE | P78334 | 6/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.39 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22136186 | 0.82 | GABRP (0.56) | GABRDGABRA1GABRB2GABRA4GABRP | |
| SCHEMBL17544036 | 0.76 | SHBG (0.39) | HSD11B1GABRDGABRA1GABRB2GABRA4 | |
| SCHEMBL7315413 | 0.73 | GABRA1 (0.71) | GABRDGABRA1GABRB2GABRA4GABRP | |
| SCHEMBL22033067 | 0.73 | GABRA1 (0.71) | GABRDGABRA1GABRB2GABRA4GABRP | |
| SCHEMBL3115466 | 0.73 | GABRA1 (0.71) | GABRDGABRA1GABRB2GABRA4GABRP | |
| SCHEMBL29904074 | 0.73 | GABRP (0.31) | GABRDGABRA1GABRB2GABRA4GABRP | |
| SCHEMBL22136187 | 0.72 | GABRP (0.55) | GABRDGABRA1GABRB2GABRA4GABRP | |
| SCHEMBL8054689 | 0.70 | SRD5A2 (0.36) | HSD11B1SRD5A2 | |
| SCHEMBL17544394 | 0.70 | POLB (0.42) | HSD11B1GABRDGABRA1GABRB2GABRA4 | |
| SCHEMBL17543919 | 0.70 | GRIN1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186267-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016029888-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2016-03-03 | — | — | WO | disclosed |