Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549656 | 0.94 | SLC6A4 (0.70) | SLC6A4SLC6A3HTR1AKMT2AMEN1 | |
| SCHEMBL17549667 | 0.85 | SLC6A4 (0.67) | SLC6A4SLC6A3HTR1AKMT2AATM | |
| SCHEMBL28066404 | 0.82 | TSHR (0.63) | HTR1AKMT2AMEN1ATMSIGMAR1 | |
| SCHEMBL7993207 | 0.81 | HTR1A (0.65) | SLC6A4SLC6A3HTR1ALMNADRD2 | |
| SCHEMBL7721328 | 0.78 | SLC6A4 (1.00) | SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL11077830 | 0.77 | SLC6A4 (0.98) | SLC6A4SLC6A3HTR1AKMT2AMEN1 | |
| SCHEMBL17549665 | 0.76 | KMT2A (0.65) | SLC6A4SLC6A3HTR1AKMT2ASIGMAR1 | |
| SCHEMBL16026463 | 0.75 | KMT2A (0.83) | SLC6A4SLC6A3HTR1AKMT2ASIGMAR1 | |
| SCHEMBL20039912 | 0.75 | OPRD1 (0.64) | SLC6A3KMT2AMEN1LMNADRD2 | |
| Hydrochloric Acid SCHEMBL7934846 | 0.74 | KMT2A (0.83) | SLC6A4SLC6A3HTR1AKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060235-A1 | Therapeutic Agent for Type 2 Diabetes | NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060235-A1 | Therapeutic Agent for Type 2 Diabetes | RNASE1, CDKL2, CDKL1 | SLC6A4 4717/4885SLC6A3 3762/4885HTR1A 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.