Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BAX | Q07812 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL27761425 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1GAALTA4H | |
| SCHEMBL27618720 | 0.81 | GABRA1 (0.39) | GABRA1GABRB2MEN1KMT2AGAA | |
| SCHEMBL10525766 | 0.81 | GABRA1 (0.39) | GABRA1GABRB2MEN1KMT2AGAA | |
| SCHEMBL3264284 | 0.80 | FOLH1 (0.41) | GABRA1GABRB2MEN1KMT2AGAA | |
| SCHEMBL7656115 | 0.80 | GABRA1 (0.40) | GABRA1GABRB2AKR1B1MEN1KMT2A | |
| SCHEMBL3739900 | 0.78 | GABRA1 (0.50) | GABRA1GABRB2AKR1B1MEN1KMT2A | |
| SCHEMBL981489 | 0.78 | KDM4E (0.47) | GABRA1GABRB2AKR1B1GAAKDM4E | |
| SCHEMBL28577075 | 0.78 | HTT (0.37) | GABRA1GABRB2MEN1KMT2AGAA | |
| SCHEMBL6546165 | 0.78 | PTK2B (0.38) | GABRA1GABRB2MEN1KMT2AGAA | |
| SCHEMBL774629 | 0.77 | HRH1 (0.44) | KDM4EALDH1A1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006071674-A2 | ORAL CARE COMPOSITIONS CONTAINING A EUCALYPTUS EXTRACT | COLGATE-PALMOLIVE COMPANY (US) | 2006-07-06 | — | — | WO | claimed |
| US-20060140883-A1 | Oral care compositions containing a eucalyptus extract | COLGATE-PALMOLIVE COMPANY | 2006-06-29 | — | — | US | claimed |
| EP-2424488-B1 | MICROENCAPSULATED COMPOSITIONS AND METHODS FOR TISSUE MINERALIZATION | PREMIER DENTAL PRODUCTS CO (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3237069-A1 | ORAL CARE COMPOSITIONS | Kiromic, LLC (US) | 2017-11-01 | — | — | EP | disclosed |
| CN-107260575-A | High water content oral cavity composition comprising microcrystalline cellulose and carboxymethyl cellulose | 高露洁-棕榄公司 | 2017-10-20 | — | — | CN | disclosed |
| EP-2866774-B1 | HIGH WATER CONTENT ORAL COMPOSITIONS COMPRISING MICROCRYSTALLINE CELLULOSE AND CARBOXYMETHYLCELLULOSE | COLGATE PALMOLIVE CO (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9724541-B2 | Dental cleaning and polishing composition comprising diamond particles | Kao, Lisa Marie (US) | 2017-08-08 | — | — | US | disclosed |
| WO-2016106313-A1 | ORAL CARE COMPOSITIONS | KIROMIC, LLC (US) | 2016-06-30 | — | — | WO | disclosed |
| CN-103118651-B | For microencapsulation compositions and the method for tissue mineralization | PREMIER DENTAL PRODUCTS COMPNAY (US) | 2016-01-06 | — | — | CN | disclosed |
| US-20150164769-A1 | High Water Content Oral Compositions Comprising Microcrystalline Cellulose and Carboxymethylcellulose | COLGATE-PALMOLIVE COMPANY (US) | 2015-06-18 | — | — | US | disclosed |
| EP-2866774-A1 | HIGH WATER CONTENT ORAL COMPOSITIONS COMPRISING MICROCRYSTALLINE CELLULOSE AND CARBOXYMETHYLCELLULOSE | Colgate-Palmolive Company (US) | 2015-05-06 | — | — | EP | disclosed |
| WO-2006071755-A1 | OREGANO ORAL CARE COMPOSITIONS AND METHODS OF USE THEREOF | COLGATE-PALMOLIVE COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006071677-A2 | INSTANT TOOTH WHITENING WITH SILICONE RESIN AND SILICONE ADHESIVE | COLGATE-PALMOLIVE COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006068750-A1 | ANTI-CARIES ORAL CARE COMPOSITION WITH XYLITOL | COLGATE-PALMOLIVE COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
| US-20060140884-A1 | Oregano oral care compositions and methods of use thereof | COLGATE-PALMOLIVE COMPANY | 2006-06-29 | — | — | US | disclosed |
| US-20060140883-A1 | Oral care compositions containing a eucalyptus extract | COLGATE-PALMOLIVE COMPANY | 2006-06-29 | — | — | US | disclosed |
| WO-2006068753-A1 | ANTI-CARIES ORAL CARE COMPOSITION WITH A CHELATING AGENT | COLGATE-PALMOLIVE COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
| US-20060142411-A1 | Instant tooth whitening with silicone resin and silicone adhesive | COLGATE-PALMOLIVE COMPANY | 2006-06-29 | — | — | US | disclosed |
| US-20060134020-A1 | Anti-caries oral care composition with a chelating agent | COLGATE-PALMOLIVE COMPANY | 2006-06-22 | — | — | US | disclosed |
| WO-2005077326-A1 | TOOTH COATING COMPOSITIONS AND METHODS | COLGATE-PALMOLIVE COMPANY (US) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060140883-A1 | Oral care compositions containing a eucalyptus extract | ELANE, MLEC, TAS2R40 | GABRA1 4471/4885GABRB2 4813/4885AKR1B1 4830/4885 |
| US-20150164769-A1 | High Water Content Oral Compositions Comprising Microcrystalline Cellulose and Carboxymethylcellulose | SI, COL14A1, COL2A1 | GABRA1 4854/4885GABRB2 4879/4885AKR1B1 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.