SCHEMBL17565658

SCHEMBL17565658

CC(C)c1nnc(S(C)(=O)=O)o1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838325 0.72 EPHX2 (0.33) ALDH1A1MAPT
SCHEMBL7485036 0.70 NOTUM (0.35) NOTUM
SCHEMBL7038707 0.70 NOTUM (0.35) NOTUM
SCHEMBL7019329 0.67 MAPT (0.35) ALDH1A1LMNAMAPTHTTHSD17B10
SCHEMBL17635541 0.64
SCHEMBL21899214 0.64 PIK3CA (0.35)
SCHEMBL15331086 0.62 EPHX2 (0.30)
SCHEMBL23558509 0.62
SCHEMBL20283648 0.62
SCHEMBL22623129 0.62 PKM (0.42) ALDH1A1MAPTPKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed
US-20190350940-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF XLINK THERAPEUTICS, INC. 2019-11-21 US disclosed
US-10342801-B2 Platinum compounds, compositions, and uses thereof PLACON THERAPEUTICS, INC. (US) 2019-07-09 US disclosed
US-10322137-B2 Platinum compounds, compositions, and uses thereof PLACON THERAPEUTICS, INC. (US) 2019-06-18 US disclosed
US-20180221508-A1 COMPOSITIONS AND METHODS FOR IMMUNOMODULATION TVA (ABC), LLC 2018-08-09 US disclosed
US-20180221503-A1 COMPOSITIONS AND METHODS FOR IMMUNO-ONCOLOGY THERAPIES TVA (ABC), LLC 2018-08-09 US disclosed
US-20180186823-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF XLINK THERAPEUTICS, INC. 2018-07-05 US disclosed
US-20180186823-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF XLINK THERAPEUTICS, INC. 2018-07-05 US disclosed
US-9937187-B2 Platinum compounds, compositions, and uses thereof PLACON THERAPEUTICS, INC. (US) 2018-04-10 US disclosed
US-20180008614-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF XLINK THERAPEUTICS, INC. 2018-01-11 US disclosed
US-20160317549-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF XLINK THERAPEUTICS, INC. 2016-11-03 US disclosed
US-9403858-B2 Platinum compounds, compositions, and uses thereof PLACON THERAPEUTICS, INC. (US) 2016-08-02 US disclosed
US-20160068557-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF XLINK THERAPEUTICS, INC. 2016-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160068557-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF BID, PDCD1LG2, CD274 IDH1 254/4885ALDH1A1 4272/4885LMNA 3727/4885
US-20180221503-A1 COMPOSITIONS AND METHODS FOR IMMUNO-ONCOLOGY THERAPIES CD47, FCGR3B, FCGR1A IDH1 786/4885ALDH1A1 1932/4885LMNA 4477/4885
US-10342801-B2 Platinum compounds, compositions, and uses thereof TP53, MSH2, FANCI IDH1 7/4885ALDH1A1 3219/4885LMNA 3047/4885
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 IDH1 2127/4885ALDH1A1 1330/4885LMNA 1652/4885
US-10322137-B2 Platinum compounds, compositions, and uses thereof BID, PDCD1LG2, CD274 IDH1 254/4885ALDH1A1 4272/4885LMNA 3727/4885
US-20180221508-A1 COMPOSITIONS AND METHODS FOR IMMUNOMODULATION CD47, ICOS, PBK IDH1 2028/4885ALDH1A1 3727/4885LMNA 4298/4885
US-20180008614-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF BID, PDCD1LG2, CD274 IDH1 254/4885ALDH1A1 4272/4885LMNA 3727/4885
US-20180186823-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF PDCD1LG2, CXCR3, CD274 IDH1 413/4885ALDH1A1 4486/4885LMNA 4166/4885
US-20160317549-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF BID, PDCD1LG2, CD274 IDH1 254/4885ALDH1A1 4272/4885LMNA 3727/4885
US-20190350940-A1 PLATINUM COMPOUNDS, COMPOSITIONS, AND USES THEREOF TP53, MSH2, FANCI IDH1 7/4885ALDH1A1 3219/4885LMNA 3047/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 IDH1 2933/4885ALDH1A1 2528/4885LMNA 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.