Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 1/20 | 0.77 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.77 |
| ▸ | THPO | P40225 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | GLA | P06280 | 1/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.77 |
| ▸ | NPY1R | P25929 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | NPY2R | P49146 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373726 | 0.89 | ADORA3 (0.69) | BMPR1BSLC29A1LMNATSHRNFKB1 | |
| SCHEMBL8373729 | 0.89 | ADORA3 (0.69) | BMPR1BSLC29A1LMNATSHRNFKB1 | |
| SCHEMBL29501810 | 0.89 | SLC29A1 (0.69) | BMPR1BSLC29A1LMNATSHRNFKB1 | |
| SCHEMBL13302978 | 0.87 | BMPR1B (1.00) | BMPR1BSLC29A1LMNATSHRNFKB1 | |
| SCHEMBL13325770 | 0.87 | BMPR1B (1.00) | BMPR1BSLC29A1LMNATSHRNFKB1 | |
| SCHEMBL6909853 | 0.87 | LMNA (0.72) | SLC29A1LMNATSHRNFKB1THPO | |
| SCHEMBL17301042 | 0.87 | LMNA (0.72) | SLC29A1LMNATSHRNFKB1THPO | |
| SCHEMBL17889837 | 0.87 | LMNA (0.72) | SLC29A1LMNATSHRNFKB1THPO | |
| SCHEMBL233209 | 0.87 | LMNA (0.72) | SLC29A1LMNATSHRNFKB1THPO | |
| SCHEMBL21953578 | 0.87 | LMNA (0.72) | SLC29A1LMNATSHRNFKB1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943760-B2 | Non-nucleotide composition for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100197913-A1 | NON-NUCLEOTIDE COMPOSITION FOR INHIBITING PLATELET AGGREGATION | PLOURDE JR ROBERT | 2010-08-05 | — | — | US | disclosed |
| US-7749980-B2 | Non-nucleotide compositions and method for treating pain | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-7749981-B2 | Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| EP-1685135-B1 | TETRAHYDRO-FURO[3,4-d]DIOXOLE COMPOUNDS AND COMPOSITIONS AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS INC (US) | 2010-05-26 | — | — | EP | disclosed |
| US-7592445-B2 | Non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1943261-A2 | DRUG-ELUTING STENTS COATED WITH NON-NUCLEOTIDE P2Y12 RECEPTOR ANTAGONIST COMPOUND | Inspire Pharmaceuticals, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| US-7368438-B2 | Non-nucleotide compositions and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| US-20080103304-A1 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | PLOURDE ROBERT JR | 2008-05-01 | — | — | US | disclosed |
| US-7335648-B2 | Non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| EP-1883637-A2 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | Inspire Pharmaceuticals, Inc. (US) | 2008-02-06 | — | — | EP | disclosed |
| US-20070123544-A1 | Non-nucleotide compositions and method for treating pain | INSPIRE PHARMACEUTICALS, INC. | 2007-05-31 | — | — | US | disclosed |
| WO-2007056217-A2 | DRUG-ELUTING STENTS COATED WITH NON-NUCLEOTIDE P2Y12 RECEPTOR ANTAGONIST COMPOUND | INSPIRE PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2006119507-A2 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| EP-1685135-A1 | TETRAHYDRO-FURO¬3,4-D|DIOXOLE COMPOUNDS AND COMPOSITIONS AND METHOD FOR INHIBITING PLATELET AGGREGATION | Inspire Pharmaceuticals, Inc. (US) | 2006-08-02 | — | — | EP | disclosed |
| US-20060121086-A1 | Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound | INSPIRE PHARMACEUTICALS, INC. | 2006-06-08 | — | — | US | disclosed |
| US-20050267134-A1 | Non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. | 2005-12-01 | — | — | US | disclosed |
| US-20050159388-A1 | Non-nucleotide compositions and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. | 2005-07-21 | — | — | US | disclosed |
| WO-2005040174-A1 | TETRAHYDRO-FURO`3,4-D!DIOXOLE COMPOUNDS AND COMPOSITIONS AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103304-A1 | NON-NUCLEOTIDE COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | P2RY12, P2RY11, P2RY13 | BMPR1B 2540/4885SLC29A1 172/4885LMNA 1834/4885 |
| US-20050267134-A1 | Non-nucleotide composition and method for inhibiting platelet aggregation | P2RY12, P2RY11, P2RY13 | BMPR1B 2286/4885SLC29A1 157/4885LMNA 1785/4885 |
| US-20100197913-A1 | NON-NUCLEOTIDE COMPOSITION FOR INHIBITING PLATELET AGGREGATION | P2RY12, P2RY13, P2RY11 | BMPR1B 2502/4885SLC29A1 163/4885LMNA 1977/4885 |
| US-20070123544-A1 | Non-nucleotide compositions and method for treating pain | P2RX3, P2RX5, P2RX1 | BMPR1B 1652/4885SLC29A1 141/4885LMNA 2063/4885 |
| US-20050159388-A1 | Non-nucleotide compositions and method for inhibiting platelet aggregation | P2RY12, P2RY11, P2RY13 | BMPR1B 2458/4885SLC29A1 188/4885LMNA 1956/4885 |
| US-20060121086-A1 | Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound | P2RY12, P2RY11, P2RY13 | BMPR1B 2524/4885SLC29A1 694/4885LMNA 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.