Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384681 | 0.92 | ALDH1A1 (0.61) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL10248081 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL30566839 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TSHREPHX2HSD17B10POLB | |
| Hydrochloric Acid SCHEMBL25370641 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHREPHX2POLBSMN1; SMN2 | |
| SCHEMBL14552719 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL8253328 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8254024 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14950072 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL2634441 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL1847712 | 0.73 | HSD11B1 (0.42) | ALDH1A1TSHREPHX2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242327-B2 | Analgesic compounds | RECURIUM IP HOLDINGS, LLC (US) | 2022-02-08 | — | — | US | disclosed |
| EP-3193855-B1 | BICYCLIC COMPOUNDS | RECURIUM IP HOLDINGS LLC (US) | 2021-05-19 | — | — | EP | disclosed |
| US-10975035-B2 | Bicyclic compounds | RECURIUM IP HOLDINGS, LLC (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200270221-A1 | ANALGESIC COMPOUNDS | KTHERA, LLC | 2020-08-27 | — | — | US | disclosed |
| US-20190233377-A1 | BICYCLIC COMPOUNDS | Zeno Royalties & Milestones, LLC | 2019-08-01 | — | — | US | disclosed |
| US-10308609-B2 | Bicyclic compounds | Zeno Royalties & Milestones, LLC (US) | 2019-06-04 | — | — | US | disclosed |
| US-20160075654-A1 | BICYCLIC COMPOUNDS | RECURIUM IP HOLDINGS, LLC | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270221-A1 | ANALGESIC COMPOUNDS | INA, IK, ACHE | ALDH1A1 144/4885TSHR 3914/4885EPHX2 194/4885 |
| US-11242327-B2 | Analgesic compounds | INA, IK, ACHE | ALDH1A1 144/4885TSHR 3914/4885EPHX2 194/4885 |
| US-20190233377-A1 | BICYCLIC COMPOUNDS | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885EPHX2 420/4885 |
| US-20160075654-A1 | BICYCLIC COMPOUNDS | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885EPHX2 420/4885 |
| US-10975035-B2 | Bicyclic compounds | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885EPHX2 420/4885 |
| US-10308609-B2 | Bicyclic compounds | OPRK1, OPRM1, OPRL1 | ALDH1A1 289/4885TSHR 3809/4885EPHX2 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.