SCHEMBL17586277

SCHEMBL17586277

CC(C)C12CC(C(=O)O)(C1)C2

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 2/20 0.54
RAB9A P51151 1/20 0.32
FFAR3 O14843 1/20 0.32
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23904374 0.83 GRM1 (0.43) GRM1FFAR3
SCHEMBL22279317 0.80 GRM1 (0.50) GRM1RAB9A
SCHEMBL27041706 0.80 GRM1 (0.61) GRM1RAB9A
SCHEMBL12308358 0.77 GRM1 (0.37) GRM1FFAR3
SCHEMBL20252858 0.77 PKM (0.52) GRM1
SCHEMBL15746432 0.75 GRIN2D (0.52) GRM1
SCHEMBL24806526 0.74 GRM1 (0.54) GRM1
SCHEMBL24907421 0.73 THRB (0.39) GRM1RAB9A
SCHEMBL9142496 0.73 GRM1 (0.50) GRM1FFAR3
SCHEMBL1648486 0.73 GRM1 (0.50) GRM1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50643-E1 Benzamide compounds RECURIUM IP HOLDINGS, LLC (US) 2025-10-21 US disclosed
EP-4556469-A1 BENZAMIDE COMPOUNDS Recurium IP Holdings, LLC (US) 2025-05-21 EP disclosed
EP-3740487-B1 BENZAMIDE COMPOUNDS AS BCI INHIBITORS FOR THE TREATMENT OF HIV RECURIUM IP HOLDINGS LLC (US) 2025-01-08 EP disclosed
US-20240180899-A1 BENZAMIDE COMPOUNDS RECURIUM IP HOLDINGS, LLC 2024-06-06 US disclosed
CN-118084904-A Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2024-05-28 CN disclosed
CN-111801327-B Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2024-02-09 CN disclosed
US-11813259-B2 Benzamide compounds RECURIUM IP HOLDINGS, LLC (US) 2023-11-14 US disclosed
US-11813260-B1 Benzamide compounds RECURIUM IP HOLDINGS, LLC (US) 2023-11-14 US disclosed
US-20230159504-A1 7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) VERTEX PHARMACEUTICALS INCORPORATED 2023-05-25 US disclosed
US-11590126-B2 Benzamide compounds RECURIUM IP HOLDINGS, LLC (US) 2023-02-28 US disclosed
WO-2021007303-A1 NANOPARTICLE FORMULATION OF BCL-2 INHIBITOR RECURIUM IP HOLDINGS, LLC (US) 2021-01-14 WO disclosed
EP-3740487-A1 BENZAMIDE COMPOUNDS Recurium IP Holdings, LLC (US) 2020-11-25 EP disclosed
EP-3737672-A1 BENZAMIDE COMPOUNDS Recurium IP Holdings, LLC (US) 2020-11-18 EP disclosed
EP-3737681-A1 BENZAMIDE COMPOUNDS Recurium IP Holdings, LLC (US) 2020-11-18 EP disclosed
US-20200338071-A1 BENZAMIDE COMPOUNDS ZENO MANAGEMENT, INC. 2020-10-29 US disclosed
US-20200339605-A1 BENZAMIDE COMPOUNDS ZENO MANAGEMENT, INC. 2020-10-29 US disclosed
CN-111801327-A Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2020-10-20 CN disclosed
CN-111801320-A Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2020-10-20 CN disclosed
CN-111788203-A Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2020-10-16 CN disclosed
US-20160075654-A1 BICYCLIC COMPOUNDS RECURIUM IP HOLDINGS, LLC 2016-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11813259-B2 Benzamide compounds MKI67, TMBIM6, HDAC1 GRM1 4827/4885RAB9A 1631/4885FFAR3 4030/4885
US-11813260-B1 Benzamide compounds MKI67, TMBIM6, HDAC1 GRM1 4827/4885RAB9A 1631/4885FFAR3 4030/4885
US-11590126-B2 Benzamide compounds MKI67, TMBIM6, HDAC1 GRM1 4827/4885RAB9A 1631/4885FFAR3 4030/4885
US-20160075654-A1 BICYCLIC COMPOUNDS OPRK1, OPRM1, OPRL1 GRM1 636/4885RAB9A 1622/4885FFAR3 3045/4885
US-20200339605-A1 BENZAMIDE COMPOUNDS MKI67, TMBIM6, HDAC1 GRM1 4827/4885RAB9A 1631/4885FFAR3 4030/4885
US-20240180899-A1 BENZAMIDE COMPOUNDS MKI67, TMBIM6, HDAC1 GRM1 4827/4885RAB9A 1631/4885FFAR3 4030/4885
US-20200338071-A1 BENZAMIDE COMPOUNDS MKI67, TMBIM6, HDAC1 GRM1 4827/4885RAB9A 1631/4885FFAR3 4030/4885
US-20230159504-A1 7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) SERPINA2, SERPINB1, SERPINE1 GRM1 3781/4885RAB9A 1761/4885FFAR3 4786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.