SCHEMBL175934

SCHEMBL175934

CC(=O)Nc1ccc(/C=C/c2ccc(N=C=S)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD51 Q06609 5/20 0.81
RAD1 O60671 1/20 0.72
P2RY6 Q15077 1/20 0.72
ENPP2 Q13822 2/20 0.67
APEX1 P27695 1/20 0.58
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 3/20 0.54
MAPT P10636 3/20 0.54
USP2 O75604 2/20 0.54
LTA P01374 2/20 0.54
CYP3A4 P08684 2/20 0.54
HPGD P15428 2/20 0.54
P2RX3 P56373 2/20 0.54
HSD17B10 Q99714 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
SENP3 Q9H4L4 4/20 0.42
SENP2 Q9HC62 4/20 0.42
SENP1 Q9P0U3 4/20 0.42
SUMO2 P61956 3/20 0.42
SUMO1 P63165 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351606 1.00 RAD51 (0.81) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL25796 1.00 RAD51 (0.81) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL2333703 0.99 RAD51 (0.80) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL2333711 0.99 RAD51 (0.80) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL30160852 0.99 RAD51 (0.80) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL15823509 0.99 RAD51 (0.80) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL5616054 0.92 RAD51 (0.70) RAD51RAD1P2RY6ENPP2APEX1
Acridine SCHEMBL6290391 0.90 RAD51 (0.67) RAD51RAD1P2RY6ENPP2APEX1
Acridine SCHEMBL722533 0.90 RAD51 (0.67) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL4857681 0.89 ENPP2 (0.69) RAD51RAD1P2RY6ENPP2APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 814 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535901-B2 Probe for detecting and treating virus YONSEI UNIVERSITY INDUSTRY FOUNDATION (YONSEI UIF) (KR) 2022-12-27 US claimed
US-20190331690-A1 BIOTHIOL DETECTION COMPOSITION COMPRISING REDOX REGULATION PROTENIN INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2019-10-31 US claimed
US-20190093180-A1 PROBE FOR DETECTING AND TREATING VIRUS YONSEI UNIVERSITY INDUSTRY FOUNDATION (YONSEI UIF) (KR) 2019-03-28 US claimed
US-20190000791-A1 ISOTHIOCYANATOSTILBENES AS A NOVEL METHOD AND PRODUCT FOR TREATING CANCER Board of Supervisors for the University of Louisiana System 2019-01-03 US claimed
EP-2934110-B1 USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS UNIV GENT (BE) 2018-08-01 EP claimed
EP-2671570-B1 MAGNETIC NANOPARTICLE, HAVING A CURIE TEMPERATURE WHICH IS WITHIN BIOCOMPATIBLE TEMPERATURE RANGE, AND METHOD FOR PREPARING SAME UNIV KOREA RES & BUS FOUND (KR) 2018-05-30 EP claimed
US-20140024683-A1 CHLORIDE CHANNEL AND CHLORIDE TRANSPORTER MODULATORS FOR THERAPY IN SMOOTH MUSCLE DISEASES NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2014-01-23 US claimed
EP-2671570-A2 MAGNETIC NANOPARTICLE, HAVING A CURIE TEMPERATURE WHICH IS WITHIN BIOCOMPATIBLE TEMPERATURE RANGE, AND METHOD FOR PREPARING SAME Korea University Research and Business Foundation (KR) 2013-12-11 EP claimed
US-20130309702-A1 MAGNETIC NANOPARTICLE, HAVING A CURIE TEMPERATURE WHICH IS WHITHIN BIOCOMPATIBLE TEMPERATURE RANGE, AND METHOD FOR PREPARING SAME KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2013-11-21 US claimed
US-8372593-B2 Method for detecting misfolded proteins and prions ADLYFE, INC. (US) 2013-02-12 US claimed
WO-2003008638-A2 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BIDNING SYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2003-01-30 WO claimed
EP-0620822-B1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS INC (US) 2001-05-30 EP claimed
EP-1067134-A2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS, INC. (US) 2001-01-10 EP claimed
US-6162603-A Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2000-12-19 US claimed
US-5932614-A VIRICIDES AGAINST HIV MERRELL PHARMACEUTICALS INC. (US) 1999-08-03 US claimed
US-5565322-A PHOTOELECTRIC DEVICES; DETECTORS; MEDICAL DIAGNOSIS NANOGEN, INC. (US) 1996-10-15 US claimed
US-5532129-A Self-organizing molecular photonic structures based on chromophore- and fluorophore-containing polynucleotides and methods of their use ENTERPRISE PARTNERS II, L.P. (US) 1996-07-02 US claimed
US-5494932-A AIDS, RETROVIRUSES, HERPES VIRUSES, CYTOMEGALOVIRUS MERRELL DOW PHARMACEUTICALS INC. (US) 1996-02-27 US claimed
EP-0498095-B1 Sulfonic stilbene derivatives in the treatment of viral diseases MERRELL DOW PHARMA (US) 1995-01-04 EP claimed
EP-0498095-A1 Sulfonic stilbene derivatives in the treatment of viral diseases MERRELL DOW PHARMACEUTICALS INC. (US) 1992-08-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140024683-A1 CHLORIDE CHANNEL AND CHLORIDE TRANSPORTER MODULATORS FOR THERAPY IN SMOOTH MUSCLE DISEASES CLCN2, SLC6A1, SLC26A3 RAD51 4871/4885RAD1 4885/4885P2RY6 709/4885
US-20190000791-A1 ISOTHIOCYANATOSTILBENES AS A NOVEL METHOD AND PRODUCT FOR TREATING CANCER SI, PCMT1, HDAC8 RAD51 4231/4885RAD1 3425/4885P2RY6 3825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.