SCHEMBL2333703

SCHEMBL2333703

CC(=O)Nc1ccc(/C=C/c2ccc(N=C=S)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1.[NaH].[NaH]

nearest known ligand 0.98

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD51 Q06609 5/20 0.80
RAD1 O60671 1/20 0.70
P2RY6 Q15077 1/20 0.70
ENPP2 Q13822 2/20 0.66
APEX1 P27695 1/20 0.57
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 3/20 0.53
MAPT P10636 3/20 0.53
USP2 O75604 2/20 0.53
LTA P01374 2/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 2/20 0.53
P2RX3 P56373 2/20 0.53
HSD17B10 Q99714 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
SENP3 Q9H4L4 4/20 0.42
SENP2 Q9HC62 4/20 0.42
SENP1 Q9P0U3 4/20 0.42
SUMO2 P61956 3/20 0.42
SUMO1 P63165 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15823509 1.00 RAD51 (0.80) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL175934 0.99 RAD51 (0.81) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL29351606 0.99 RAD51 (0.81) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL25796 0.99 RAD51 (0.81) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL2333711 0.98 RAD51 (0.80) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL30160852 0.98 RAD51 (0.80) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL5616054 0.91 RAD51 (0.70) RAD51RAD1P2RY6ENPP2APEX1
Acridine SCHEMBL6290391 0.89 RAD51 (0.67) RAD51RAD1P2RY6ENPP2APEX1
Acridine SCHEMBL722533 0.89 RAD51 (0.67) RAD51RAD1P2RY6ENPP2APEX1
SCHEMBL4857676 0.88 ENPP2 (0.69) RAD51RAD1P2RY6ENPP2APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240000084-A1 ANTIPATHOGENIC AGENT, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN DISPOSAL DEVICE, ANTIPATHOGENIC AGENT PRODUCTION METHOD, ANTIBACTERIAL TREATMENT METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN DISPOSAL METHOD ACENET INC. (JP) 2024-01-04 US disclosed
US-20230263710-A1 ORAL CARE AGENT OSAKA UNIVERSITY (JP) 2023-08-24 US disclosed
EP-4230042-A1 ANTIPATHOGENIC DRUG, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN PROCESSING DEVICE, METHOD FOR PRODUCING ANTIPATHOGENIC DRUG, ANTIBACTERIAL METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN PROCESSING METHOD Acenet Inc. (JP) 2023-08-23 EP disclosed
US-20230181628-A1 EPITHELIAL CANCER THERAPEUTIC AGENT OSAKA UNIVERSITY (JP) 2023-06-15 US disclosed
EP-4147703-A1 EPITHELIAL CANCER THERAPEUTIC AGENT OSAKA UNIVERSITY (JP) 2023-03-15 EP disclosed
US-20200171118-A1 RADICAL GENERATING CATALYST, METHOD FOR PRODUCING RADICAL, METHOD FOR PRODUCING OXIDATION REACTION PRODUCT, DRUG, AND DRUG FOR USE IN AGRICULTURE AND LIVESTOCK INDUSTRY ACENET INC. (JP) 2020-06-04 US disclosed
EP-3626339-A1 RADICAL-GENERATING CATALYST, RADICAL PRODUCTION METHOD, OXIDATION REACTION PRODUCT PRODUCTION METHOD, CHEMICAL AGENT, AND CHEMICAL AGENT FOR AGRICULTURE AND LIVESTOCK Acenet Inc. (JP) 2020-03-25 EP disclosed
US-20130189280-A1 PROTEIN DOMAINS AND USES THEREFOR SYDNEY WEST AREA HEALTH SERVICE (SWAHS) (AU) 2013-07-25 US disclosed
EP-2533794-A1 PROTEIN DOMAINS AND USES THEREFOR The University Of Sydney (AU) 2012-12-19 EP disclosed
WO-2011097688-A1 PROTEIN DOMAINS AND USES THEREFOR THE UNIVERSITY OF SYDNEY (AU) 2011-08-18 WO disclosed
US-5512667-A Trifunctional intermediates for preparing 3'-tailed oligonucleotides DRUG ROYALTY LP1 (CA) 1996-04-30 US disclosed
US-5419966-A Solid support for synthesis of 3'-tailed oligonucleotides MICROPROBE CORPORATION (US) 1995-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263710-A1 ORAL CARE AGENT TAS2R39, TAS2R40, TAS2R45 RAD51 2257/4885RAD1 3191/4885P2RY6 3452/4885
US-20200171118-A1 RADICAL GENERATING CATALYST, METHOD FOR PRODUCING RADICAL, METHOD FOR PRODUCING OXIDATION REACTION PRODUCT, DRUG, AND DRUG FOR USE IN AGRICULTURE AND LIVESTOCK INDUSTRY PRDX2, PRDX1, PRDX5 RAD51 1869/4885RAD1 3102/4885P2RY6 1080/4885
US-20230181628-A1 EPITHELIAL CANCER THERAPEUTIC AGENT EPCAM, EGFR, MUC1 RAD51 669/4885RAD1 1888/4885P2RY6 4514/4885
US-20240000084-A1 ANTIPATHOGENIC AGENT, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN DISPOSAL DEVICE, ANTIPATHOGENIC AGENT PRODUCTION METHOD, ANTIBACTERIAL TREATMENT METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN DISPOSAL METHOD EIF2AK2, HAO2, ZC3HAV1 RAD51 1411/4885RAD1 298/4885P2RY6 1998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.