Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 8/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 3/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599385 | 0.79 | TSHR (0.47) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599338 | 0.78 | FABP4 (0.42) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599392 | 0.78 | CCKBR (0.47) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599355 | 0.78 | PTK2B (0.43) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599399 | 0.77 | PTK2B (0.57) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599305 | 0.76 | ACLY (0.55) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599333 | 0.76 | PTK2B (0.52) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599387 | 0.76 | FABP4 (0.56) | FABP4PTK2BSMN1; SMN2ACLY | |
| SCHEMBL17599320 | 0.76 | SMN1; SMN2 (0.54) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 | |
| SCHEMBL17599374 | 0.76 | PTK2B (0.56) | FABP4PTK2BSMN1; SMN2ACLYSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998294-A1 | Naphthyl sulfonamide phenyl derivatives as KEAP-1 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |