Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.41 |
| ▸ | HEXB | P07686 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 6/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457221 | 0.78 | SMN1; SMN2 (0.42) | HEXAHEXBRAB9AKDM4ENPC1 | |
| SCHEMBL17599659 | 0.70 | HEXA (0.42) | HEXAHEXBKIF11GFERRAB9A | |
| SCHEMBL457066 | 0.69 | KDM4E (0.40) | HEXAHEXBKIF11GFERRAB9A | |
| SCHEMBL25833757 | 0.67 | SCN2A (0.55) | — | |
| SCHEMBL455369 | 0.66 | KIF11 (0.42) | HEXAHEXBKIF11KDM4E | |
| SCHEMBL456853 | 0.66 | HEXA (0.38) | HEXAHEXBKIF11LTA4HCTSS | |
| SCHEMBL28827850 | 0.65 | HEXA (0.46) | HEXAHEXBKIF11CTSSCTSK | |
| SCHEMBL9145018 | 0.65 | RAB9A (0.48) | HEXAHEXBKIF11GFERRAB9A | |
| SCHEMBL1687449 | 0.64 | MAOB (0.57) | HEXAHEXBKIF11 | |
| SCHEMBL17541744 | 0.64 | RAB9A (0.59) | HEXAHEXBKIF11GFERRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-B1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-03-23 | — | — | EP | disclosed |