Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 6/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458020 | 0.79 | KDM4E (0.43) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL17599658 | 0.69 | HEXA (0.41) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL462512 | 0.67 | NR1H4 (0.49) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL17541744 | 0.67 | RAB9A (0.59) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL16364806 | 0.65 | AOC3 (0.51) | KDM4ENPC1POLBRAB9AATM | |
| SCHEMBL1687449 | 0.64 | MAOB (0.57) | HEXAHEXBKIF11MAOB | |
| SCHEMBL8990814 | 0.64 | MAOB (0.61) | KIF11MAOB | |
| SCHEMBL4637026 | 0.64 | NR1H2 (0.40) | KDM4ENPC1POLBRAB9ANOTUM | |
| SCHEMBL13410633 | 0.61 | KIF11 (0.78) | KIF11MAOB | |
| SCHEMBL197238 | 0.61 | KIF11 (0.78) | KIF11MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |