Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17601979 | 0.88 | CHRNA7 (0.43) | CARM1MAPTMAPK1 | |
| SCHEMBL22761235 | 0.82 | ACHE (0.38) | — | |
| SCHEMBL22761232 | 0.81 | ACHE (0.38) | MAPTALDH1A1 | |
| SCHEMBL17601999 | 0.80 | ADRA2A (0.41) | TSHRHPGDMAPK1HSD17B10 | |
| SCHEMBL16002508 | 0.79 | HTR1A (0.36) | MAOBMAOA | |
| SCHEMBL22761237 | 0.78 | ACHE (0.36) | — | |
| SCHEMBL22271831 | 0.77 | ACHE (0.52) | MAOBMAOAMAPTHPGDMAPK1 | |
| SCHEMBL17602004 | 0.77 | MAOA (0.35) | MAOBMAOAHPGD | |
| SCHEMBL17601996 | 0.77 | ABCB1 (0.40) | ALDH1A1 | |
| SCHEMBL22760876 | 0.76 | ACHE (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | claimed |
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-24 | — | — | US | claimed |
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | disclosed |
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-24 | — | — | US | disclosed |
| CN-103145617-A | Phenanthridine derivative as well as medicinal composition, preparation method and application thereof | KUNMING INST BOTANY CN ACAD | 2013-06-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CTNNB1, WNT3A, WNT1 | CARM1 4319/4885CHEK1 4580/4885MAOB 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.