Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.42 |
| ▸ | GCGR | P47871 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604614 | 0.75 | MAPK14 (0.46) | MAPK14GSK3BMAPK13MAPK12MAPK11 | |
| SCHEMBL17686564 | 0.75 | PHF8 (0.66) | MAPK14PHF8 | |
| SCHEMBL5371873 | 0.71 | KDM4E (0.67) | MAPK14GSK3BMAPK13MAPK12MAPK11 | |
| SCHEMBL17604530 | 0.70 | MAPK14 (0.35) | MAPK14GSK3BMAPK13MAPK12MAPK11 | |
| SCHEMBL27335373 | 0.70 | MAPK14 (0.69) | MAPK14GSK3BMAPK13MAPK12MAPK11 | |
| SCHEMBL105252 | 0.69 | RAB9A (0.40) | GSK3BALOX5CLK4 | |
| SCHEMBL30574759 | 0.68 | IDO1 (0.51) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL23416081 | 0.67 | MAPK14 (0.47) | MAPK14 | |
| SCHEMBL7089424 | 0.65 | MAPK14 (0.46) | MAPK14GSK3BMAPK13MAPK12MAPK11 | |
| SCHEMBL18041684 | 0.65 | TGFBR1 (0.53) | MAPK14GSK3BMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |