Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | GPR6 | P46095 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760885 | 0.88 | RBP4 (0.40) | RBP4GPR6FAAHTP53MAPT | |
| SCHEMBL1761060 | 0.86 | FAAH (0.40) | RBP4HSD17B1HSD17B2EPHX2FAAH | |
| SCHEMBL1761045 | 0.84 | ACHE (0.39) | EPHX2GPR6FAAHPDCD1LG2CD274 | |
| SCHEMBL1761072 | 0.84 | ACHE (0.39) | EPHX2GPR6FAAHPDCD1LG2CD274 | |
| SCHEMBL1761008 | 0.83 | KDM4E (0.37) | EPHX2GPR6FAAHPDCD1LG2CD274 | |
| SCHEMBL1761013 | 0.83 | HSD17B10 (0.44) | GPR6FAAHPDGFRBADORA2AMAPT | |
| SCHEMBL1760990 | 0.82 | PKM (0.41) | FAAHPDGFRB | |
| SCHEMBL1761069 | 0.81 | FAAH (0.42) | RBP4EPHX2FAAHPDCD1LG2CD274 | |
| SCHEMBL1761054 | 0.80 | FAAH (0.52) | RBP4FAAHPDCD1LG2CD274LMNA | |
| SCHEMBL1761028 | 0.79 | FAAH (0.47) | FAAHLMNAADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947692-B2 | Substituted thiazolo[5,4-d]pyrimidine urea derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-05-24 | — | — | US | disclosed |