Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 8/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17659 | 0.87 | KMO (0.30) | KMO | |
| SCHEMBL29607 | 0.79 | ADRB1 (0.38) | TAS2R14ADRB1SYKKMO | |
| SCHEMBL17379 | 0.76 | L3MBTL1 (0.36) | KMO | |
| SCHEMBL18344 | 0.74 | KMO (0.67) | KMO | |
| SCHEMBL19455822 | 0.73 | ADRB1 (0.35) | TAS2R14ADRB1SYKIDH1KMO | |
| SCHEMBL5314947 | 0.73 | HDAC4 (0.37) | HDAC4TAS2R14SYK | |
| SCHEMBL1578122 | 0.73 | KMO (0.54) | TAS2R14SYKKMOPKM | |
| SCHEMBL22637356 | 0.72 | IDO1 (0.43) | HDAC4 | |
| SCHEMBL13837225 | 0.71 | SYK (0.45) | HDAC4TAS2R14ADRB1SYKKMO | |
| SCHEMBL31537115 | 0.71 | TAS2R14 (0.42) | HDAC4TAS2R14ADRB1SYKKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269340-A | KCNT1 inhibitors and methods of use | 普拉克西斯精密药物股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |