Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613646 | 0.89 | TSHR (0.37) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL12023038 | 0.81 | TSHR (0.46) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL17613638 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL17613692 | 0.76 | TSHR (0.36) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL17613702 | 0.75 | TSHR (0.35) | TSHRALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL17613686 | 0.75 | DNM1 (0.34) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL17613695 | 0.72 | TSHR (0.36) | TSHRALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL17613649 | 0.72 | TSHR (0.36) | TSHRALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL14231681 | 0.72 | — | — | |
| SCHEMBL17613731 | 0.71 | THRA (0.31) | THRBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |